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The beneficial effect of alpha-blockers for ureteral stent-related discomfort: systematic review and network meta-analysis for alfuzosin versus tamsulosin versus placebo
DC Field | Value | Language |
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dc.contributor.author | 이주용 | - |
dc.contributor.author | 조강수 | - |
dc.contributor.author | 최영득 | - |
dc.contributor.author | 함원식 | - |
dc.date.accessioned | 2016-02-04T11:26:56Z | - |
dc.date.available | 2016-02-04T11:26:56Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140447 | - |
dc.description.abstract | BACKGROUND: This study was carried out a network meta-analysis of evidence from randomized controlled trials (RCTs) to evaluate stent-related discomfort in patients with alfuzosin or tamsulosin versus placebo. METHODS: Relevant RCTs were identified from electronic databases. The proceedings of appropriate meetings were also searched. Seven articles on the basis of RCTs were included in our meta-analysis. Using pairwise and network meta-analyses, comparisons were made by qualitative and quantitative syntheses. Evaluation was performed with the Ureteric Stent Symptoms Questionnaire to assess the urinary symptom score (USS) and body pain score (BPS). RESULTS: One of the seven RCTs was at moderate risk of bias for all quality criteria; two studies had a high risk of bias. In the network meta-analysis, both alfuzosin (mean difference [MD];-4.85, 95 % confidence interval [CI];-8.53--1.33) and tamsulosin (MD;-8.84, 95 % CI;-13.08--4.31) showed lower scores compared with placebo; however, the difference in USS for alfuzosin versus tamsulosin was not significant (MD; 3.99, 95 % CI;-1.23-9.04). Alfuzosin (MD;-5.71, 95 % CI;-11.32--0.52) and tamsulosin (MD;-7.77, 95 % CI;-13.68--2.14) showed lower scores for BPS compared with placebo; however, the MD between alfuzosin and tamsulosin was not significant (MD; 2.12, 95 % CI;-4.62-8.72). In the rank-probability test, tamsulosin ranked highest for USS and BPS, and alfuzosin was second. CONCLUSION: The alpha-blockers significantly decreased USS and BPS in comparison with placebo. Tamsulosin might be more effective than alfuzosin. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 55 | - |
dc.relation.isPartOf | BMC UROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adrenergic alpha-Antagonists/administration & dosage* | - |
dc.subject.MESH | Bayes Theorem | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Pain/drug therapy* | - |
dc.subject.MESH | Pain/etiology | - |
dc.subject.MESH | Pain Measurement | - |
dc.subject.MESH | Quinazolines/administration & dosage* | - |
dc.subject.MESH | Randomized Controlled Trials as Topic | - |
dc.subject.MESH | Stents/adverse effects* | - |
dc.subject.MESH | Sulfonamides/administration & dosage* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Ureteral Obstruction/diagnosis | - |
dc.subject.MESH | Ureteral Obstruction/therapy | - |
dc.title | The beneficial effect of alpha-blockers for ureteral stent-related discomfort: systematic review and network meta-analysis for alfuzosin versus tamsulosin versus placebo | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨기과학) | - |
dc.contributor.googleauthor | Jong Kyou Kwon | - |
dc.contributor.googleauthor | Kang Su Cho | - |
dc.contributor.googleauthor | Cheol Kyu Oh | - |
dc.contributor.googleauthor | Dong Hyuk Kang | - |
dc.contributor.googleauthor | Hyungmin Lee | - |
dc.contributor.googleauthor | Won Sik Ham | - |
dc.contributor.googleauthor | Young Deuk Choi | - |
dc.contributor.googleauthor | Joo Yong Lee | - |
dc.identifier.doi | 10.1186/s12894-015-0050-5 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03161 | - |
dc.contributor.localId | A03801 | - |
dc.contributor.localId | A04111 | - |
dc.contributor.localId | A04337 | - |
dc.relation.journalcode | J00379 | - |
dc.identifier.eissn | 1471-2490 | - |
dc.identifier.pmid | 26104313 | - |
dc.subject.keyword | Ureter | - |
dc.subject.keyword | Stents | - |
dc.subject.keyword | Adrenergic alpha-antagonists | - |
dc.subject.keyword | Meta-analysis | - |
dc.subject.keyword | Bayes theorem | - |
dc.contributor.alternativeName | Lee, Joo Yong | - |
dc.contributor.alternativeName | Cho, Kang Su | - |
dc.contributor.alternativeName | Choi, Young Deuk | - |
dc.contributor.alternativeName | Ham, Won Sik | - |
dc.contributor.affiliatedAuthor | Lee, Joo Yong | - |
dc.contributor.affiliatedAuthor | Cho, Kang Su | - |
dc.contributor.affiliatedAuthor | Choi, Young Deuk | - |
dc.contributor.affiliatedAuthor | Ham, Won Sik | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 15 | - |
dc.citation.startPage | 55 | - |
dc.identifier.bibliographicCitation | BMC UROLOGY, Vol.15 : 55, 2015 | - |
dc.identifier.rimsid | 29908 | - |
dc.type.rims | ART | - |
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