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Age at First Delivery and Osteoporosis Risk in Korean Postmenopausal Women: The 2008–2011 Korea National Health and Nutrition Examination Survey (KNHANES)

DC Field Value Language
dc.contributor.author최윤락-
dc.contributor.author서석교-
dc.contributor.author윤보현-
dc.contributor.author이병석-
dc.contributor.author조시현-
dc.contributor.author최영식-
dc.date.accessioned2016-02-04T11:21:55Z-
dc.date.available2016-02-04T11:21:55Z-
dc.date.issued2015-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140262-
dc.description.abstractIt has been reported in several studies that there may be a significant correlation between reproductive history and the risk of osteoporosis due to the effect of estrogen. Under this hypothesis, however, it is unclear whether the age at first delivery has any major influences on the risk of osteoporosis. Therefore, this study aimed to investigate the relationship between the age at first delivery and the risk of osteoporosis in Korean menopausal women. This study was performed using data from the 2008-2011 Korea National Health and Nutrition Examination Survey and included 2,530 Korean postmenopausal women. The diagnosis of osteoporosis was made using the World Health Organization T-score criteria (T-score ≤ -2.5, at the femoral neck or lumbar spine). Participants were categorized into 3 groups according to age at first delivery: ≤ 23, 24-29, and ≥ 30 years. Older age, lower body mass index, lower calcium intake, later menarche, and earlier menopause increased the risk of osteoporosis, whereas hormone therapy and oral contraceptive use were associated with a decreased risk of osteoporosis. Postmenopausal women whose first delivery occurred at age 24-29 years were shown to have a significantly increased risk of osteoporosis (odds ratio, 2.124; 95% confidence interval, 1.096-4.113; P = 0.026) compared to those who first gave birth after the age of 30 years. These findings suggest that postmenopausal women whose first delivery occurred in their mid to late 20s, a period during which bone mass slowly accumulates to the peak, are at an increased risk of osteoporosis.-
dc.description.statementOfResponsibilityopen-
dc.format.extente0123665-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBody Mass Index-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMaternal Age*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNutrition Surveys-
dc.subject.MESHOsteoporosis, Postmenopausal/epidemiology*-
dc.subject.MESHPostmenopause-
dc.subject.MESHReproductive History-
dc.subject.MESHRepublic of Korea-
dc.titleAge at First Delivery and Osteoporosis Risk in Korean Postmenopausal Women: The 2008–2011 Korea National Health and Nutrition Examination Survey (KNHANES)-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Orthopedic Surgery (정형외과학)-
dc.contributor.googleauthorBo Hyon Yun-
dc.contributor.googleauthorYun Rak Choi-
dc.contributor.googleauthorYoung Sik Choi-
dc.contributor.googleauthorSiHyun Cho-
dc.contributor.googleauthorByung Seok Lee-
dc.contributor.googleauthorSeok Kyo Seo-
dc.identifier.doi10.1371/journal.pone.0123665-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04136-
dc.contributor.localIdA01888-
dc.contributor.localIdA02555-
dc.contributor.localIdA02795-
dc.contributor.localIdA03846-
dc.contributor.localIdA04114-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid25946162-
dc.contributor.alternativeNameChoi, Yun Rak-
dc.contributor.alternativeNameSeo, Seok Kyo-
dc.contributor.alternativeNameYun, Bo Hyon-
dc.contributor.alternativeNameLee, Byung Seok-
dc.contributor.alternativeNameCho, Si Hyun-
dc.contributor.alternativeNameChoi, Young Sik-
dc.contributor.affiliatedAuthorChoi, Yun Rak-
dc.contributor.affiliatedAuthorSeo, Seok Kyo-
dc.contributor.affiliatedAuthorYun, Bo Hyon-
dc.contributor.affiliatedAuthorLee, Byung Seok-
dc.contributor.affiliatedAuthorCho, Si Hyun-
dc.contributor.affiliatedAuthorChoi, Young Sik-
dc.rights.accessRightsfree-
dc.citation.volume10-
dc.citation.number5-
dc.citation.startPagee0123665-
dc.identifier.bibliographicCitationPLOS ONE, Vol.10(5) : e0123665, 2015-
dc.identifier.rimsid50385-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers

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