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Titanium surface modification by using microwave-induced argon plasma in various conditions to enhance osteoblast biocompatibility

Authors
 Gyeung Mi Seon  ;  Hyok Jin Seo  ;  Soon Young Kwon  ;  Mi Hee Lee  ;  Byeong Ju Kwon  ;  Min Sung Kim  ;  Min Ah Koo  ;  Bong Joo Park  ;  Jong Chul Park 
Citation
 Biomaterials Research, Vol.19(2) : 76-82, 2015 
Journal Title
 Biomaterials Research 
ISSN
 1226-4601 
Issue Date
2015
Abstract
BACKGROUND: Titanium is a well proven implantable material especially for osseointegratable implants by its biocompatibility and anti-corrosive surface properties. Surface characteristics of the implant play an important role for the evolution of bone tissue of the recipient site. Among the various surface modification methods, plasma treatment is one of the promising methods for enhance biocompatibility. We made microwave-induced argon plasma at atmospheric pressure to improve in titanium surface biocompatibility. RESULTS: Various states of emission spectra from excited species-argon, nitrogen atoms and oxygen atoms were observed. The electron energy band structures are the unique characteristics of atoms and functional groups. Microwave-induced argon plasma treatment changed the titanium surface to be very hydrophilic especially on the 5 s short treatment and 30 s, 90 s long treatment samples that detected by contact angle measurement. MC3T3-E1 attachment and proliferation assay significantly increased in 5 s at short treatment, 30 s, and 90 s at long treatment after 5 days incubation. CONCLUSIONS: Result indicated that microwave-induce argon plasma treatment would be an effective method to modify titanium surface for enhancing cell-material interactions.
Files in This Item:
T201501542.pdf Download
DOI
10.1186/s40824-015-0034-2
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
구민아(Koo, Min-Ah) ORCID logo https://orcid.org/0000-0002-8671-1131
권병주(Kwon, Byeong-Ju) ORCID logo https://orcid.org/0000-0001-9916-0546
김민성(Kim, Min Sung)
박종철(Park, Jong Chul) ORCID logo https://orcid.org/0000-0003-0083-5991
서혁진(Seo, Hyok Jin)
선경미(Seon, Gyeung Mi)
이미희(Lee, Mi Hee) ORCID logo https://orcid.org/0000-0002-9630-7044
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/140174
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