Cited 0 times in
Primary diffuse leptomeningeal gliosarcomatosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강석구 | - |
dc.contributor.author | 김세훈 | - |
dc.contributor.author | 김의현 | - |
dc.contributor.author | 장종희 | - |
dc.date.accessioned | 2016-02-04T11:16:13Z | - |
dc.date.available | 2016-02-04T11:16:13Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2288-2405 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140048 | - |
dc.description.abstract | Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition with a fatal outcome, characterized by diffuse infiltration of the leptomeninges by neoplastic glial cells without evidence of primary tumor in the brain or spinal cord parenchyma. In particular, PDLG histologically diagnosed as gliosarcoma is extremely rare, with only 2 cases reported to date. We report a case of primary diffuse leptomeningeal gliosarcomatosis. A 68-year-old man presented with fever, chilling, headache, and a brief episode of mental deterioration. Initial T1-weighted post-contrast brain magnetic resonance imaging (MRI) showed diffuse leptomeningeal enhancement without a definite intraparenchymal lesion. Based on clinical and imaging findings, antiviral treatment was initiated. Despite the treatment, the patient's neurologic symptoms and mental status progressively deteriorated and follow-up MRI showed rapid progression of the disease. A meningeal biopsy revealed gliosarcoma and was conclusive for the diagnosis of primary diffuse leptomeningeal gliosarcomatosis. We suggest the inclusion of PDLG in the potential differential diagnosis of patients who present with nonspecific neurologic symptoms in the presence of leptomeningeal involvement on MRI. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 34~38 | - |
dc.relation.isPartOf | Brain Tumor Research and Treatment | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Primary diffuse leptomeningeal gliosarcomatosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | Ju Hyung Moon | - |
dc.contributor.googleauthor | Se Hoon Kim | - |
dc.contributor.googleauthor | Eui Hyun Kim | - |
dc.contributor.googleauthor | Seok-Gu Kang | - |
dc.contributor.googleauthor | Jong Hee Chang | - |
dc.identifier.doi | 10.14791/btrt.2015.3.1.34 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00036 | - |
dc.contributor.localId | A00610 | - |
dc.contributor.localId | A00837 | - |
dc.contributor.localId | A03470 | - |
dc.relation.journalcode | J00398 | - |
dc.identifier.pmid | 25977905 | - |
dc.subject.keyword | Glioma, gliosarcoma | - |
dc.subject.keyword | Leptomeningeal carcinomatosis | - |
dc.subject.keyword | Meningoencephalitis | - |
dc.contributor.alternativeName | Kang, Seok Gu | - |
dc.contributor.alternativeName | Kim, Se Hoon | - |
dc.contributor.alternativeName | Kim, Eui Hyun | - |
dc.contributor.alternativeName | Chang, Jong Hee | - |
dc.contributor.affiliatedAuthor | Kang, Seok Gu | - |
dc.contributor.affiliatedAuthor | Kim, Se Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Eui Hyun | - |
dc.contributor.affiliatedAuthor | Chang, Jong Hee | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 3 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 34 | - |
dc.citation.endPage | 38 | - |
dc.identifier.bibliographicCitation | Brain Tumor Research and Treatment, Vol.3(1) : 34-38, 2015 | - |
dc.identifier.rimsid | 45595 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.