Cited 27 times in
Helicobacter pylori Eradication on the Prevention of Metachronous Lesions after Endoscopic Resection of Gastric Neoplasm: A Meta-Analysis
DC Field | Value | Language |
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dc.contributor.author | 김지현 | - |
dc.contributor.author | 박준철 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 정다현 | - |
dc.contributor.author | 정현수 | - |
dc.date.accessioned | 2016-02-04T11:15:57Z | - |
dc.date.available | 2016-02-04T11:15:57Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140038 | - |
dc.description.abstract | BACKGROUND: There is controversy about the effect of Helicobacter pylori (H. pylori) eradication on the prevention of metachronous gastric cancer after endoscopic resection (ER). AIMS: The aim of this study was to systematically evaluate the effect of H. pylori eradication on the prevention of metachronous gastric lesions after ER of gastric neoplasms. METHODS: We performed a systematic search of PubMed, EMBASE, the Cochrane Library, and MEDLINE that encompassed studies through April 2014. Our meta-analysis consisted of 10 studies, which included 5881 patients who underwent ER of gastric neoplasms. RESULTS: When we compared the incidence of metachronous lesions between H. pylori-eradicated and non-eradicated groups, H. pylori eradication significantly lowered the risk of metachronous lesions after ER of gastric neoplasms (five studies, OR = 0.392, 95% CI 0.259 - 0.593, P < 0.001). When we compared H. pylori-eradicated and persistent groups, again, H. pylori eradication significantly lowered the incidence of metachronous lesions after ER of gastric neoplasms (six studies, OR = 0.468, 95% CI 0.326 - 0.673, P < 0.001). There was no obvious heterogeneity across the analyzed studies. CONCLUSIONS: This meta-analysis suggests a preventive role for H. pylori eradication for metachronous gastric lesions after ER of gastric neoplasms. Thus, H. pylori eradication should be considered if H. pylori infection is confirmed during ER. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | e0124725 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anti-Bacterial Agents/therapeutic use | - |
dc.subject.MESH | Gastroscopy | - |
dc.subject.MESH | Helicobacter Infections/complications* | - |
dc.subject.MESH | Helicobacter Infections/drug therapy | - |
dc.subject.MESH | Helicobacter Infections/microbiology | - |
dc.subject.MESH | Helicobacter pylori* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Neoplasms, Second Primary/epidemiology | - |
dc.subject.MESH | Neoplasms, Second Primary/etiology* | - |
dc.subject.MESH | Neoplasms, Second Primary/prevention & control* | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Publication Bias | - |
dc.subject.MESH | Stomach Neoplasms/etiology* | - |
dc.subject.MESH | Stomach Neoplasms/surgery | - |
dc.title | Helicobacter pylori Eradication on the Prevention of Metachronous Lesions after Endoscopic Resection of Gastric Neoplasm: A Meta-Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Da Hyun Jung | - |
dc.contributor.googleauthor | Jie-Hyun Kim | - |
dc.contributor.googleauthor | Hyun Soo Chung | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Sung Kwan Shin | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.identifier.doi | 10.1371/journal.pone.0124725 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A03591 | - |
dc.contributor.localId | A00996 | - |
dc.relation.journalcode | J02540 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.pmid | 25915048 | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Jung, Da Hyun | - |
dc.contributor.alternativeName | Chung, Hyun Soo | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Shin, Sung Kwan | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Jung, Da Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 10 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | e0124725 | - |
dc.identifier.bibliographicCitation | PLOS ONE, Vol.10(4) : e0124725, 2015 | - |
dc.identifier.rimsid | 45588 | - |
dc.type.rims | ART | - |
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