0 194

Cited 6 times in

Golgi polarization plays a role in the directional migration of neonatal dermal fibroblasts induced by the direct current electric fields

Authors
 Min Sung Kim  ;  Mi Hee Lee  ;  Byeong-Ju Kwon  ;  Min-Ah Koo  ;  Gyeung Mi Seon  ;  Jong-Chul Park 
Citation
 Biochemical and Biophysical Research Communications, Vol.460(2) : 255-260, 2015 
Journal Title
 Biochemical and Biophysical Research Communications 
ISSN
 0006-291X 
Issue Date
2015
Abstract
Directional cell migration requires cell polarization. The reorganization of the Golgi apparatus is an important phenomenon in the polarization and migration of many types of cells. Direct current electric fields (dc (EF) induced directional cell migration in a wide variety of cells. Here nHDFs migrated toward cathode under 1 V/cm dc EF, however 1 μM of brefeldin A (BFA) inhibited the dc EF induced directional migration. BFA (1 μM) did not cause the complete Golgi dispersal for 2 h. When the Golgi polarization maintained their direction of polarity, the direction of cell migration also kept toward the same direction of the Golgi polarization even though the dc EF was reversed. In this study, the importance of the Golgi polarization in the directional migration of nHDf under dc EF was identified.
Full Text
http://www.sciencedirect.com/science/article/pii/S0006291X15004568
DOI
10.1016/j.bbrc.2015.03.021
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
구민아(Koo, Min-Ah) ORCID logo https://orcid.org/0000-0002-8671-1131
권병주(Kwon, Byeong-Ju) ORCID logo https://orcid.org/0000-0001-9916-0546
김민성(Kim, Min Sung)
박종철(Park, Jong Chul) ORCID logo https://orcid.org/0000-0003-0083-5991
선경미(Seon, Gyeung Mi)
이미희(Lee, Mi Hee) ORCID logo https://orcid.org/0000-0002-9630-7044
Export
RIS (EndNote)
XLS (Excel)
XML
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139966
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse