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Neointimal response to second-generation drug-eluting stents in diabetic patients with de-novo coronary lesions: intravascular ultrasound study

DC FieldValueLanguage
dc.contributor.author고영국-
dc.contributor.author권혁문-
dc.contributor.author민필기-
dc.contributor.author원호연-
dc.contributor.author윤영원-
dc.contributor.author이병권-
dc.contributor.author장양수-
dc.contributor.author홍범기-
dc.date.accessioned2016-02-04T11:12:37Z-
dc.date.available2016-02-04T11:12:37Z-
dc.date.issued2015-
dc.identifier.issn0954-6928-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139911-
dc.description.abstractOBJECTIVES: The aim of this study was to evaluate the extent of neointimal response after the implantation of a second-generation drug-eluting stent, zotarolimus-eluting stent (ZES-ER, Endeavor Resolute) or everolimus-eluting stent (EES, Xience V), using intravascular ultrasound (IVUS) in diabetic patients. MATERIALS AND METHODS: In all, 154 diabetic patients with de-novo coronary lesions were randomized to be implanted with a ZES-ER or EES, and the angiographic follow-up at 9 months combined with a complete IVUS study was available for 96 patients with 101 lesions. RESULTS: Baseline demographic and lesion parameters were similar in both groups at index percutaneous coronary intervention. On follow-up angiography, in-stent late lumen loss and minimal lumen diameter were not different between the two groups. On IVUS study, neointimal hyperplasia volume [median (interquartile range): ZES-ER vs. EES; 2.25 mm (0.57-6.25) vs. 1.59 mm (0.45-8.37), P=0.615] and in-stent percentage of volume obstruction [median (interquartile range): ZES-ER vs. EES; 1.16% (0.33-3.61) vs. 0.77% (0.29-4.01), P=0.615] showed similar results between the two groups. CONCLUSION: In diabetic patients, the second-generation drug-eluting stents, ZES-ER and EES, were comparable in inhibiting neointimal proliferation.-
dc.description.statementOfResponsibilityopen-
dc.format.extent212~219-
dc.relation.isPartOfCORONARY ARTERY DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHCardiovascular Agents/administration & dosage*-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Restenosis/diagnostic imaging-
dc.subject.MESHCoronary Restenosis/etiology-
dc.subject.MESHCoronary Restenosis/pathology-
dc.subject.MESHCoronary Restenosis/prevention & control*-
dc.subject.MESHCoronary Vessels/diagnostic imaging-
dc.subject.MESHCoronary Vessels/drug effects*-
dc.subject.MESHCoronary Vessels/pathology-
dc.subject.MESHDiabetic Angiopathies/diagnosis-
dc.subject.MESHDiabetic Angiopathies/therapy*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHEverolimus/administration & dosage-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeointima*-
dc.subject.MESHPercutaneous Coronary Intervention/adverse effects-
dc.subject.MESHPercutaneous Coronary Intervention/instrumentation*-
dc.subject.MESHPilot Projects-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHProsthesis Design-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRisk Factors-
dc.subject.MESHSirolimus/administration & dosage-
dc.subject.MESHSirolimus/analogs & derivatives-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUltrasonography, Interventional*-
dc.titleNeointimal response to second-generation drug-eluting stents in diabetic patients with de-novo coronary lesions: intravascular ultrasound study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorWon, Hoyoun-
dc.contributor.googleauthorKang, Tae Soo-
dc.contributor.googleauthorHong, Bum-Kee-
dc.contributor.googleauthorLee, Seunghwan-
dc.contributor.googleauthorJeon, Dong Woon-
dc.contributor.googleauthorRyu, Sung Kee-
dc.contributor.googleauthorMin, Pil-Ki-
dc.contributor.googleauthorYoon, Young Won-
dc.contributor.googleauthorLee, Byoung Kwon-
dc.contributor.googleauthorKwon, Hyuck Moon-
dc.contributor.googleauthorKo, Young-Guk-
dc.contributor.googleauthorJang, Yangsoo-
dc.identifier.doi10.1097/MCA.0000000000000195-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00127-
dc.contributor.localIdA00260-
dc.contributor.localIdA01412-
dc.contributor.localIdA02448-
dc.contributor.localIdA02580-
dc.contributor.localIdA02793-
dc.contributor.localIdA03448-
dc.contributor.localIdA04394-
dc.relation.journalcodeJ00649-
dc.identifier.eissn1473-5830-
dc.identifier.pmid25426659-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00019501-201505000-00005&LSLINK=80&D=ovft-
dc.subject.keyworddiabetes mellitus-
dc.subject.keywordeverolimus-eluting stent-
dc.subject.keywordintravascular ultrasound-
dc.subject.keywordzotarolimus-eluting stent-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKwon, Hyuck Moon-
dc.contributor.alternativeNameMin, Pil Ki-
dc.contributor.alternativeNameWon, Ho Youn-
dc.contributor.alternativeNameYoon, Young Won-
dc.contributor.alternativeNameLee, Byoung Kwon-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameHong, Bum Kee-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKwon, Hyuck Moon-
dc.contributor.affiliatedAuthorMin, Pil Ki-
dc.contributor.affiliatedAuthorWon, Ho Youn-
dc.contributor.affiliatedAuthorYoon, Young Won-
dc.contributor.affiliatedAuthorLee, Byoung Kwon-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorHong, Bum Kee-
dc.rights.accessRightsnot free-
dc.citation.volume26-
dc.citation.number3-
dc.citation.startPage212-
dc.citation.endPage219-
dc.identifier.bibliographicCitationCORONARY ARTERY DISEASE, Vol.26(3) : 212-219, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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