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Effect of a second injection of botulinum toxin on lower facial contouring, as evaluated using 3-dimensional laser scanning

 Lee, Hong-Hee  ;  Kim, Seong Taek  ;  Lee, Kee-Joon  ;  Baik, Hyoung-Seon 
 DERMATOLOGIC SURGERY, Vol.41(4) : 439-444, 2015 
Journal Title
Issue Date
Adult ; Botulinum Toxins, Type A/administration & dosage* ; Facial Asymmetry/diagnosis* ; Facial Asymmetry/drug therapy* ; Female ; Follow-Up Studies ; Healthy Volunteers ; Humans ; Imaging, Three-Dimensional/methods* ; Injections, Intramuscular ; Lasers* ; Male ; Masseter Muscle ; Middle Aged ; Neuromuscular Agents/administration & dosage ; Retrospective Studies ; Young Adult
BACKGROUND: Botulinum toxin type A (BoNT-A) is widely used to improve the lower facial contour. OBJECTIVE: To determine the difference in the changes in the lower facial contour achieved with 1 and 2 sessions of BoNT-A injections using 3-dimensional (3D) laser scanning. MATERIALS AND METHODS: Twenty volunteers were randomly divided into 2 groups. Group I (n = 10) received a single injection, whereas Group II (n = 10) received 2 sessions of injections, the second being administered 4 months after the first. Each injection comprised of 25 U of BoNT-A and was administered to the masseter muscle bilaterally. Evaluation of the effect of BoNT-A injection was performed using 3D laser scan images obtained before the injection and 6 months thereafter in Group I, and before the first injection and 6 months thereafter in the Group II. RESULTS: The mean changes in the volume and thickness in Group I were -1,186 mm and -1.52 mm, respectively; the corresponding changes were -4,072 mm and -3.84 mm in Group II. The reductions were significantly greater in Group II than in Group I. CONCLUSION: The administration of a second BoNT-A injection is effective for better aesthetic results for the lower facial contour.
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2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Orthodontics (교정과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seong Taek(김성택)
Baik, Hyoung Seon(백형선)
Lee, Kee Joon(이기준) ORCID logo https://orcid.org/0000-0002-0782-3128
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