0 587

Cited 11 times in

Impact of central haemodynamics on left ventricular function in individuals with an exaggerated blood pressure response to exercise

DC Field Value Language
dc.contributor.author박성하-
dc.contributor.author심지영-
dc.contributor.author정남식-
dc.contributor.author최동훈-
dc.contributor.author하종원-
dc.contributor.author홍그루-
dc.date.accessioned2016-02-04T11:08:29Z-
dc.date.available2016-02-04T11:08:29Z-
dc.date.issued2015-
dc.identifier.issn0263-6352-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139757-
dc.description.abstractOBJECTIVE: The impact of exaggerated blood pressure response (EBPR) to exercise on left ventricular function and the mechanism of its association are poorly understood. This study investigated the impact of arterial stiffening on left ventricular function in individuals with an EBPR to exercise. We hypothesized that individuals with low pulse pressure (PP) amplification during exercise would have worse left ventricular function than those with high PP amplification in individuals with an EBPR to exercise. METHODS: Fifty-nine individuals with an EBPR to exercise (18 men, age 57 ± 12 years) and 59 age and sex-matched controls were studied. Radial artery tonometry was performed at rest and immediately after exercise during supine bicycle exercise echocardiography. RESULTS: There were no differences in left ventricular structure or function between individuals with an EBPR to exercise and controls. When individuals with an EBPR to exercise were divided into two groups on the basis of PP amplification after exercise [Group 1 (n = 30), high PP amplification after exercise; Group 2 (n = 29), low PP amplification after exercise], group 2 showed larger left atrial volume and lower early diastolic (e') and systolic (S') mitral annular velocities. Left ventricular apical rotation was also exaggerated in group 2. In multiple regression, PP amplification after exercise was an independent determinant of e' (β = 0.16, P = 0.019) and S' (β = 0.25, P = 0.009) in individuals with an EBPR to exercise. CONCLUSION: In individuals with an EBPR to exercise, the degree of left ventricular dysfunction is variable. EBPR to exercise in the presence of arterial stiffening contributes to the deterioration of left ventricular function.-
dc.description.statementOfResponsibilityopen-
dc.format.extent612~620-
dc.relation.isPartOfJOURNAL OF HYPERTENSION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHBlood Pressure/physiology*-
dc.subject.MESHEchocardiography-
dc.subject.MESHExercise/physiology*-
dc.subject.MESHExercise Test-
dc.subject.MESHFemale-
dc.subject.MESHHeart Ventricles/diagnostic imaging-
dc.subject.MESHHemodynamics/physiology*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMitral Valve/diagnostic imaging-
dc.subject.MESHMyocardial Contraction/physiology*-
dc.subject.MESHVentricular Function, Left/physiology*-
dc.titleImpact of central haemodynamics on left ventricular function in individuals with an exaggerated blood pressure response to exercise-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorGeu Rua Hong-
dc.contributor.googleauthorSungha Park-
dc.contributor.googleauthorWoo In Yang-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorNamsik Chung-
dc.contributor.googleauthorJong Won Ha-
dc.identifier.doi10.1097/HJH.0000000000000431-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01512-
dc.contributor.localIdA02213-
dc.contributor.localIdA03585-
dc.contributor.localIdA04053-
dc.contributor.localIdA04257-
dc.contributor.localIdA04386-
dc.relation.journalcodeJ01448-
dc.identifier.eissn1473-5598-
dc.identifier.pmid25479033-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004872-201503000-00025&LSLINK=80&D=ovft-
dc.subject.keywordblood pressure-
dc.subject.keywordexercise-
dc.subject.keywordhypertension-
dc.subject.keywordleft ventricular function-
dc.subject.keywordpulse pressure amplification-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.affiliatedAuthorPark, Sung Ha-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.rights.accessRightsnot free-
dc.citation.volume33-
dc.citation.number3-
dc.citation.startPage612-
dc.citation.endPage620-
dc.identifier.bibliographicCitationJOURNAL OF HYPERTENSION, Vol.33(3) : 612-620, 2015-
dc.identifier.rimsid52998-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.