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Positive reactions to nickel on a patch test do not predict clinical outcome of nickel alloy-based atrial septal defect occluder implantation

Authors
 Kim H.J.  ;  Shin J.U.  ;  Lee J.  ;  Lee H.  ;  Jin S.b  ;  Kim S.H.  ;  Noh J.Y.  ;  Lee K.H. 
Citation
 DERMATOLOGY, Vol.230(2) : 184-188, 2015 
Journal Title
DERMATOLOGY
ISSN
 1018-8665 
Issue Date
2015
MeSH
Adult ; Female ; Heart Septal Defects, Atrial/therapy ; Humans ; Hypersensitivity/diagnosis* ; Male ; Middle Aged ; Migraine Disorders/etiology ; Nickel/adverse effects* ; Patch Tests ; Predictive Value of Tests ; Retrospective Studies ; Septal Occluder Device/adverse effects* ; Titanium/adverse effects* ; Young Adult
Keywords
Atrial septal defect closure ; Nickel allergy ; Nickel-titanium alloy device ; Patch test
Abstract
BACKGROUND: Patch testing is thought to be necessary prior to metal device implantation to rule out metal allergy-related complications; however, there are controversies over the effects of nickel allergy on the outcome of nickel alloy-based device implantation.

OBJECTIVE: This study aimed to evaluate the adverse events in a Korean population of nickel allergy patients who underwent atrial septal defect (ASD) closure with a nickel-titanium alloy-based device.

METHODS: We retrospectively reviewed the medical records of patients who underwent ASD closure with a nitinol device.

RESULTS: Among 38 patients who had ASD closure, 4 of 5 nickel-allergic patients and 10 of the 33 non-nickel-allergic patients had post-closure complications. All patients fared well, without device failure culminating in device removal.

CONCLUSION: In this study, positive reactions to nickel in a patch test were not associated with adverse early or late outcomes following ASD closure with a nickel alloy-based device.
Full Text
http://www.karger.com/Article/FullText/371511
DOI
10.1159/000371511
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Jin, Shan(김산)
Kim, Seo Hyeong(김서형)
Kim, Hee Joo(김희주)
Noh, Ji Yeon(노지연)
Shin, Jung U(신정우) ORCID logo https://orcid.org/0000-0001-5259-6879
Lee, Kwang Hoon(이광훈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139589
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