371 724

Cited 14 times in

Risk factors for mortality in patients with Serratia marcescens bacteremia

DC Field Value Language
dc.contributor.author구남수-
dc.contributor.author김민형-
dc.contributor.author김재경-
dc.contributor.author김준명-
dc.contributor.author송영구-
dc.contributor.author송제은-
dc.contributor.author안진영-
dc.contributor.author안혜원-
dc.contributor.author정수진-
dc.contributor.author최준용-
dc.contributor.author최흔-
dc.contributor.author한상훈-
dc.contributor.author김정호-
dc.date.accessioned2016-02-04T11:04:01Z-
dc.date.available2016-02-04T11:04:01Z-
dc.date.issued2015-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139588-
dc.description.abstractPURPOSE: Over the last 30 years, Serratia marcescens (S. marcescens) has emerged as an important pathogen, and a common cause of nosocomial infections. The aim of this study was to identify risk factors associated with mortality in patients with S. marcescens bacteremia. MATERIALS AND METHODS: We performed a retrospective cohort study of 98 patients who had one or more blood cultures positive for S. marcescens between January 2006 and December 2012 in a tertiary care hospital in Seoul, South Korea. Multiple risk factors were compared with association with 28-day all-cause mortality. RESULTS: The 28-day mortality was 22.4% (22/98 episodes). In a univariate analysis, the onset of bacteremia during the intensive care unit stay (p=0.020), serum albumin level (p=0.011), serum C-reactive protein level (p=0.041), presence of indwelling urinary catheter (p=0.023), and Sequential Oran Failure Assessment (SOFA) score at the onset of bacteremia (p<0.001) were significantly different between patients in the fatal and non-fatal groups. In a multivariate analysis, lower serum albumin level and an elevated SOFA score were independently associated with 28-day mortality [adjusted odds ratio (OR) 0.206, 95% confidential interval (CI) 0.044-0.960, p=0.040, and adjusted OR 1.474, 95% CI 1.200-1.810, p<0.001, respectively]. CONCLUSION: Lower serum albumin level and an elevated SOFA score were significantly associated with adverse outcomes in patients with S. marcescens bacteremia.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAnti-Bacterial Agents/therapeutic use-
dc.subject.MESHBacteremia/drug therapy-
dc.subject.MESHBacteremia/microbiology-
dc.subject.MESHBacteremia/mortality*-
dc.subject.MESHCross Infection/mortality-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIntensive Care Units-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultiple Organ Failure-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSerratia Infections/diagnosis-
dc.subject.MESHSerratia Infections/drug therapy-
dc.subject.MESHSerratia Infections/mortality*-
dc.subject.MESHSerratia marcescens/drug effects-
dc.subject.MESHSerratia marcescens/isolation & purification*-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titleRisk factors for mortality in patients with Serratia marcescens bacteremia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSun Bean Kim-
dc.contributor.googleauthorYong Duk Jeon-
dc.contributor.googleauthorJung Ho Kim-
dc.contributor.googleauthorJae Kyoung Kim-
dc.contributor.googleauthorHea Won Ann-
dc.contributor.googleauthorHeun Choi-
dc.contributor.googleauthorMin Hyung Kim-
dc.contributor.googleauthorJe Eun Song-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorJune Myung Kim-
dc.identifier.doi10.3349/ymj.2015.56.2.348-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00189-
dc.contributor.localIdA00480-
dc.contributor.localIdA00856-
dc.contributor.localIdA00953-
dc.contributor.localIdA02037-
dc.contributor.localIdA02059-
dc.contributor.localIdA02267-
dc.contributor.localIdA02275-
dc.contributor.localIdA03638-
dc.contributor.localIdA04191-
dc.contributor.localIdA04227-
dc.contributor.localIdA04286-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid25683980-
dc.subject.keywordSerratia marcescens-
dc.subject.keywordbacteremia-
dc.subject.keywordmortality-
dc.subject.keywordrisk factors-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameKim, Min Hyung-
dc.contributor.alternativeNameKim, Jae Kyoung-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameSong, Je Eun-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameAnn, Hea Won-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameChoi, Heun-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.affiliatedAuthorKu, Nam Su-
dc.contributor.affiliatedAuthorKim, Min Hyung-
dc.contributor.affiliatedAuthorKim, Jae Kyoung-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorSong, Je Eun-
dc.contributor.affiliatedAuthorAhn, Jin Young-
dc.contributor.affiliatedAuthorAnn, Hea Won-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorChoi, Heun-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.rights.accessRightsfree-
dc.citation.volume56-
dc.citation.number2-
dc.citation.startPage348-
dc.citation.endPage354-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.56(2) : 348-354, 2015-
dc.identifier.rimsid56522-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.