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Fatal scedosporiosis in multiple solid organ allografts transmitted from a nearly-drowned donor

DC Field Value Language
dc.contributor.author강석민-
dc.contributor.author안진영-
dc.contributor.author윤종찬-
dc.contributor.author최준용-
dc.date.accessioned2016-02-04T11:02:14Z-
dc.date.available2016-02-04T11:02:14Z-
dc.date.issued2015-
dc.identifier.issn1600-6135-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139522-
dc.description.abstractScedosporium spp. is the most common mold infection in pneumonia resulting from near-drowning. Three fatal scedosporiosis cases developed after solid organ transplantation, probably transmitted from the nearly-drowned donor. One heart transplant recipient and two kidney transplant recipients developed fatal scedosporiosis following deceased donor transplantation from the same donor, a nearly-drowned victim of a suicide attempt. Genotypically, indistinguishable strains of Scedosporium auratiacum were recovered from the three recipients. Two liver transplant recipients from the same donor received prophylactic voriconazole without any subsequent signs of infection. To determine the safety of donation from nearly-drowned donors, a national traceback investigation was also performed of the causes of deaths in all transplant recipients who received organs from drowned donors between 2001 and 2013. Over 13 years, 2600 deceased donor transplants were performed in Korea. Among these 2600 deceased donor transplants, 27 (1%) victims of drowning donated their organs. From these 27 donors, 84 patients received organ transplants and 18 died, including the above three. We found no microbiologic evidence of invasive mold transmission from the nearly-drowned donors to the other 15 recipients. Although disseminated infection in the donor could not be demonstrated by culture, undiagnosed disseminated donor infection and transmission of Scedosporium spp. should be considered in near-drowning events.-
dc.description.statementOfResponsibilityopen-
dc.format.extent833~840-
dc.relation.isPartOfAMERICAN JOURNAL OF TRANSPLANTATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHChild, Preschool-
dc.subject.MESHDrowning*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMycoses/complications*-
dc.subject.MESHOrgan Transplantation*-
dc.subject.MESHPneumonia/complications*-
dc.subject.MESHYoung Adult-
dc.titleFatal scedosporiosis in multiple solid organ allografts transmitted from a nearly-drowned donor-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorS.-H. Kim-
dc.contributor.googleauthorY. E. Ha-
dc.contributor.googleauthorJ.-C. Youn-
dc.contributor.googleauthorJ. S. Park-
dc.contributor.googleauthorH. Sung-
dc.contributor.googleauthorM.-N. Kim-
dc.contributor.googleauthorH. J. Choi-
dc.contributor.googleauthorY.-J. Lee-
dc.contributor.googleauthorS.-M. Kang-
dc.contributor.googleauthorJ. Y. Ahn-
dc.contributor.googleauthorJ. Y. Choi-
dc.contributor.googleauthorY.-J. Kim-
dc.contributor.googleauthorS.-K. Lee-
dc.contributor.googleauthorS.-J. Kim-
dc.contributor.googleauthorK. R. Peck-
dc.contributor.googleauthorS.-O. Lee-
dc.contributor.googleauthorY.-H. Kim-
dc.contributor.googleauthorS. Hwang-
dc.contributor.googleauthorS.-G. Lee-
dc.contributor.googleauthorJ. Ha-
dc.contributor.googleauthorD.-J. Han-
dc.identifier.doi10.1111/ajt.13008-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00037-
dc.contributor.localIdA02267-
dc.contributor.localIdA02600-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ00121-
dc.identifier.eissn1600-6143-
dc.identifier.pmid25639881-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/ajt.13008/abstract-
dc.subject.keywordclinical research/practice-
dc.subject.keywordcomplication: infectious-
dc.subject.keyworddonors and donation: donor-derived infections-
dc.subject.keywordinfectious disease-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameYoun, Jong Chan-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.affiliatedAuthorKang, Seok Min-
dc.contributor.affiliatedAuthorAhn, Jin Young-
dc.contributor.affiliatedAuthorYoun, Jong Chan-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.rights.accessRightsnot free-
dc.citation.volume15-
dc.citation.number3-
dc.citation.startPage833-
dc.citation.endPage840-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF TRANSPLANTATION, Vol.15(3) : 833-840, 2015-
dc.identifier.rimsid55448-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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