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Optical coherence tomography-based predictors for creatine kinase-myocardial band elevation after elective percutaneous coronary intervention for in-stent restenosis

DC FieldValueLanguage
dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author신동호-
dc.contributor.author이승률-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author이승율-
dc.date.accessioned2016-02-04T11:01:53Z-
dc.date.available2016-02-04T11:01:53Z-
dc.date.issued2015-
dc.identifier.issn1522-1946-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139509-
dc.description.abstractOBJECTIVES: We evaluated whether morphological characteristics of neointimal tissue of in-stent restenosis (ISR) lesions assessed by optical coherence tomography (OCT) affect periprocedural elevation of creatine kinase-myocardial band (CK-MB). BACKGROUND: The impact of neointimal characteristics of ISR lesions on periprocedural myocardial injury has not been sufficiently investigated. METHODS: A total of 125 patients with ISR lesions underwent elective percutaneous coronary intervention (PCI) and pre-PCI OCT examination. Measurements of CK-MB were performed upon hospitalization, before PCI, and every 8 hr for 24 hr after PCI. CK-MB elevation was defined as levels above the 99th percentile of the upper reference limit. Neoatherosclerosis was defined as neointima with lipid or calcification. RESULTS: Post-PCI CK-MB elevation was observed in 20 (16.0%) patients. The maximum length of consecutive cross-sections with neoatherosclerosis on the longitudinal axis of the stent was significantly larger in patients with post-PCI CK-MB elevation than in those without [8.8 mm (1.5-10.4) vs. 0.0 mm (0.0-1.0), P < 0.001], and thin-cap fibroatheroma (TCFA) were more frequently observed at the site of minimal lumen cross-sectional area in patients with post-PCI CK-MB elevation (55.0% vs. 1.9%, P < 0.001). Multivariate analysis revealed that the maximum length of segments with neoatherosclerosis [odds ratio (OR), 1.463; 95% confidence interval (CI), 1.090-1.962; P = 0.011] and TCFA (OR, 14.328; 95% CI, 1.118-183.628; P = 0.041) were independent predictors for post-PCI CK-MB elevation. CONCLUSIONS: A greater axial length of neoatherosclerosis and the presence of TCFA at the most stenotic site were significantly associated with post-PCI CK-MB elevation in ISR lesions.-
dc.description.statementOfResponsibilityopen-
dc.format.extent564~572-
dc.relation.isPartOfCATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHChi-Square Distribution-
dc.subject.MESHCoronary Restenosis/diagnosis-
dc.subject.MESHCoronary Restenosis/etiology-
dc.subject.MESHCoronary Restenosis/therapy*-
dc.subject.MESHCoronary Vessels/pathology*-
dc.subject.MESHCreatine Kinase, MB Form/blood*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHNeointima-
dc.subject.MESHOdds Ratio-
dc.subject.MESHPercutaneous Coronary Intervention/adverse effects-
dc.subject.MESHPercutaneous Coronary Intervention/instrumentation*-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHRetreatment-
dc.subject.MESHRisk Factors-
dc.subject.MESHStents*-
dc.subject.MESHTime Factors-
dc.subject.MESHTomography, Optical Coherence*-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUp-Regulation-
dc.subject.MESHVascular Calcification/etiology-
dc.subject.MESHVascular Calcification/therapy-
dc.titleOptical coherence tomography-based predictors for creatine kinase-myocardial band elevation after elective percutaneous coronary intervention for in-stent restenosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSeung-Yul Lee-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorDong-Ho Shin-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi10.1002/ccd.25643-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02097-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA02922-
dc.relation.journalcodeJ00471-
dc.identifier.eissn2451-9456-
dc.identifier.pmid25158217-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/ccd.25643/abstract-
dc.subject.keywordin-stent restenosis-
dc.subject.keywordneoatherosclerosis-
dc.subject.keywordoptical coherence tomography-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameShin, Dong Ho-
dc.contributor.alternativeNameLee, Seung Yul-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorShin, Dong Ho-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorLee, Seung Yul-
dc.rights.accessRightsnot free-
dc.citation.volume85-
dc.citation.number4-
dc.citation.startPage564-
dc.citation.endPage572-
dc.identifier.bibliographicCitationCATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol.85(4) : 564-572, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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