Cited 10 times in
What are the risk factors for residual tumor cells after endoscopic complete resection in gastric epithelial neoplasia?
DC Field | Value | Language |
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dc.contributor.author | 박준철 | - |
dc.contributor.author | 박효진 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 윤각원 | - |
dc.contributor.author | 윤영훈 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 정현수 | - |
dc.contributor.author | 김지현 | - |
dc.contributor.author | 박재준 | - |
dc.date.accessioned | 2016-02-04T10:55:44Z | - |
dc.date.available | 2016-02-04T10:55:44Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0930-2794 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139289 | - |
dc.description.abstract | BACKGROUND: In early gastric cancer (EGC) and gastric adenoma, residual tumors may develop despite complete endoscopic resection (ER). To improve the chance of curative resection, we investigated the risk factors of residual tumor development in completely resected gastric epithelial neoplasia after ER. METHODS: In total, 3,879 gastric epithelial neoplasms showing complete resection after ER were examined; 46 (1.2 %) residual tumors were found upon follow-up endoscopy. Clinicopathological characteristics were evaluated between those with and without residual tumors. RESULTS: For gastric adenoma, high-grade dysplasia and severe intestinal metaplasia (IM) in the background mucosa were significantly associated with residual tumors. For EGC, poorly differentiated adenocarcinoma (PD), signet ring cell carcinoma (SRC), having a minimum lateral safety margin of <3 mm, and localization in the upper third of the stomach were significantly associated with residual tumors. Multivariate analysis revealed that a lateral safety margin of <3 mm (OR 13.8; p < 0.001), PD (OR 16.3; p = 0.014), and SRC (OR 9.8; p = 0.009) among EGC patients, and severe IM in the background mucosa (OR 9.0; p = 0.024) among gastric adenoma patients, were significantly associated with residual tumors. CONCLUSIONS: For neoplasms with undifferentiated histology (PD or SRC), short-term endoscopic follow-up may help to detect residual tumors that form after complete resection via ER. For EGC, the lateral margin may be considered safe if greater than 3 mm. However, the possibility of satellite lesions should be investigated when the gastric adenoma to be resected is surrounded by severe IM. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 487~492 | - |
dc.relation.isPartOf | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenoma/diagnosis | - |
dc.subject.MESH | Adenoma/epidemiology | - |
dc.subject.MESH | Adenoma/surgery* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gastrectomy/methods* | - |
dc.subject.MESH | Gastric Mucosa/pathology* | - |
dc.subject.MESH | Gastroscopy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Laparoscopy/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Grading* | - |
dc.subject.MESH | Neoplasm, Residual | - |
dc.subject.MESH | Postoperative Period | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stomach Neoplasms/diagnosis | - |
dc.subject.MESH | Stomach Neoplasms/epidemiology | - |
dc.subject.MESH | Stomach Neoplasms/surgery* | - |
dc.title | What are the risk factors for residual tumor cells after endoscopic complete resection in gastric epithelial neoplasia? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Gak Won Yun | - |
dc.contributor.googleauthor | Jie-Hyun Kim | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Sung Kwan Shin | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Hyun Soo Chung | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Young Hoon Youn | - |
dc.contributor.googleauthor | Hyojin Park | - |
dc.identifier.doi | 10.1007/s00464-014-3693-5 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A01774 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02538 | - |
dc.contributor.localId | A02583 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A01636 | - |
dc.contributor.localId | A00996 | - |
dc.relation.journalcode | J02703 | - |
dc.identifier.eissn | 1432-2218 | - |
dc.identifier.pmid | 25015521 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00464-014-3693-5 | - |
dc.subject.keyword | Endoscopic resection | - |
dc.subject.keyword | Gastric epithelial neoplasia | - |
dc.subject.keyword | Residual tumors | - |
dc.subject.keyword | Risk factors | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Park, Hyo Jin | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Yun, Gak Won | - |
dc.contributor.alternativeName | Youn, Young Hoon | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Chung, Hyun Soo | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.alternativeName | Park, Jae Jun | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Park, Hyo Jin | - |
dc.contributor.affiliatedAuthor | Shin, Sung Kwan | - |
dc.contributor.affiliatedAuthor | Yun, Gak Won | - |
dc.contributor.affiliatedAuthor | Youn, Young Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Park, Jae Jun | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 29 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 487 | - |
dc.citation.endPage | 492 | - |
dc.identifier.bibliographicCitation | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol.29(2) : 487-492, 2015 | - |
dc.identifier.rimsid | 45545 | - |
dc.type.rims | ART | - |
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