Cited 5 times in
Hemoglobin assay in anemic patients with a photothermal spectral-domain optical coherence reflectometric sensor
DC Field | Value | Language |
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dc.contributor.author | 김현옥 | - |
dc.date.accessioned | 2016-02-04T10:54:18Z | - |
dc.date.available | 2016-02-04T10:54:18Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139235 | - |
dc.description.abstract | BACKGROUND: We recently introduced an optical sensor, termed photothermal spectral-domain optical coherence reflectometer (PT SD-OCR), capable of direct measurement of hemoglobin concentration ([Hb]) without chemicals and pre-processing of blood. PT SD-OCR measures [Hb] by quantifying refractive index changes of blood samples due to photothermal effect under the irradiation of 532-nm light. We evaluated diagnostic accuracy and precision of PT SD-OCR in anemic patients. METHODS: We used PT SD-OCR to measure [Hb] in 50 anemic patients, and examined its accuracy against a hematology analyzer (ADVIA 2120i, Siemens AG). Its precision was assessed by examining the SD and CV based on 20 repeated measurements on 3 blood samples. Its performance was also compared with a hemoglobinometer (HemoCue 201+, HemoCue). RESULTS: The PT SD-OCR demonstrated good correspondence with the hematology analyzer with a Pearson's correlation coefficient of 0.992 and a bias of -0.055 g/dl. Standard deviation and CV were measured to be <0.25 g/dl and <2.05%. CONCLUSIONS: Simple and chemical-free operation of PT SD-OCR enabled rapid and accurate measurement of [Hb] in anemic patients. The sensor is expected to facilitate clinical procedures related to blood-related disorders in patient care. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 71~76 | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anemia/blood* | - |
dc.subject.MESH | Hemoglobins/analysis* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Thermography* | - |
dc.subject.MESH | Tomography, Optical Coherence* | - |
dc.title | Hemoglobin assay in anemic patients with a photothermal spectral-domain optical coherence reflectometric sensor | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Hun Kim | - |
dc.contributor.googleauthor | Sungwook Song | - |
dc.contributor.googleauthor | Jinyeong Yim | - |
dc.contributor.googleauthor | Hyun Ok Kim | - |
dc.contributor.googleauthor | Chulmin Joo | - |
dc.identifier.doi | 10.1016/j.cca.2014.10.001 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01122 | - |
dc.relation.journalcode | J00543 | - |
dc.identifier.eissn | 1873-3492 | - |
dc.identifier.pmid | 25312865 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S000989811400432X | - |
dc.subject.keyword | Anemia | - |
dc.subject.keyword | Hemoglobin concentration | - |
dc.subject.keyword | Optical interferometer | - |
dc.subject.keyword | Optical sensor | - |
dc.subject.keyword | Photothermal effect | - |
dc.contributor.alternativeName | Kim, Hyun Ok | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Ok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 439 | - |
dc.citation.startPage | 71 | - |
dc.citation.endPage | 76 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, Vol.439 : 71-76, 2015 | - |
dc.identifier.rimsid | 45512 | - |
dc.type.rims | ART | - |
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