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Relationship between bicuspid aortic valve phenotype, valvular function, and ascending aortic dimensions.

Authors
 Jun Seok Kim  ;  Sung Min Ko  ;  Hyun Keun Chee  ;  Je Kyoun Shin  ;  Meong Gun Song  ;  Hong Ju Shin 
Citation
 JOURNAL OF HEART VALVE DISEASE, Vol.23(4) : 406-413, 2014 
Journal Title
JOURNAL OF HEART VALVE DISEASE
ISSN
 0966-8519 
Issue Date
2014
MeSH
Adult ; Age Factors ; Aorta/pathology* ; Aortic Valve/abnormalities* ; Aortic Valve/pathology ; Aortic Valve/physiopathology ; Aortic Valve/surgery ; Dilatation, Pathologic ; Female ; Heart Valve Diseases/pathology* ; Heart Valve Diseases/physiopathology* ; Heart Valve Diseases/surgery ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Sex Factors
Abstract
Background and aim of the study: Bicuspid aortic valve (BAV) is known to be associated with aortic valve dysfunction and ascending aorta (AA) dilatation. However, the relationship between BAV morphology and AA dimensions remains unclear. Thus, the study aim was to characterize the aortic valve function and AA dimensions according to the presence of raphe and BAV phenotype. Methods: A total of 164 patients with BAV who underwent aortic valve surgery between October 2007 and November 2012 was investigated. BAV was classified as either type I (anterior-posterior orientation) or type II (right-left orientation), and subdivided as raphe+ (presence of raphe) and raphe- (no raphe). Results: Type I BAV was present in 103 patients (62.8%), and raphe+ in 100 (61.0%). Patients with raphe+ were typically younger than those with raphe-, and male gender was more predominant (88.0% and 53.1%, respectively, p <0.05). Aortic regurgitation was more common in patients with type I and raphe+ BAV, and aortic stenosis in patients with type II and raphe- BAV. In patients with raphe+, the diameters of aortic annulus related to the body surface area (BSA) were larger, and the diameters of the tubular portion of AA indexed to BSA were smaller than in patients with raphe- (p <0.05). Conclusion: BAV morphology is helpful for predicting the type of aortic valve dysfunction and the location of AA dilatation.
Full Text
http://www.icr-heart.com/?cid=3870&g=3
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Hong Ju(신홍주)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139024
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