Cited 147 times in
Obesity survival paradox in pneumonia: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | 정금지 | - |
dc.contributor.author | 지선하 | - |
dc.date.accessioned | 2015-12-28T11:10:07Z | - |
dc.date.available | 2015-12-28T11:10:07Z | - |
dc.date.issued | 2014 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138842 | - |
dc.description.abstract | BACKGROUND: It is unclear whether an 'obesity survival paradox' exists for pneumonia. Therefore, we conducted a meta-analysis to assess the associations between increased body mass index (BMI), pneumonia risk, and mortality risk. METHODS: Cohort studies were identified from the PubMed and Embase databases. Summary relative risks (RRs) with their corresponding 95% confidence intervals (CIs) were calculated using a random effects model. RESULTS: Thirteen cohort studies on pneumonia risk (n = 1,536,623), and ten cohort studies on mortality (n = 1,375,482) were included. Overweight and obese individuals were significantly associated with an increased risk of pneumonia (RR = 1.33, 95% CI 1.04 to 1.71, P = 0.02, I(2) = 87%). In the dose-response analysis, the estimated summary RR of pneumonia per 5 kg/m(2) increase in BMI was 1.04 (95% CI 1.01 to 1.07, P = 0.01, I(2) = 84%). Inversely, overweight and obese subjects were significantly associated with reduced risk of pneumonia mortality (RR = 0.83, 95% CI 0.77 to 0.91, P < 0.01, I(2) = 34%). The estimated summary RR of mortality per 5 kg/m(2) increase in BMI was 0.95 (95% CI 0.93 to 0.98, P < 0.01, I(2) = 77%). CONCLUSIONS: This meta-analysis suggests that an 'obesity survival paradox' exists for pneumonia. Because this meta-analysis is based on observational studies, more studies are required to confirm the results. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 61 | - |
dc.relation.isPartOf | BMC MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Body Mass Index* | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Confidence Intervals | - |
dc.subject.MESH | Databases, Factual | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Obesity/complications | - |
dc.subject.MESH | Obesity/mortality* | - |
dc.subject.MESH | Observational Studies as Topic | - |
dc.subject.MESH | Overweight/complications | - |
dc.subject.MESH | Overweight/mortality | - |
dc.subject.MESH | Pneumonia/complications | - |
dc.subject.MESH | Pneumonia/mortality* | - |
dc.subject.MESH | Risk | - |
dc.subject.MESH | Risk Reduction Behavior | - |
dc.title | Obesity survival paradox in pneumonia: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.college | Graduate School of Public Health (보건대학원) | - |
dc.contributor.department | Graduate School of Public Health (보건대학원) | - |
dc.contributor.googleauthor | Wei Nie | - |
dc.contributor.googleauthor | Yi Zhang | - |
dc.contributor.googleauthor | Sun Ha Jee | - |
dc.contributor.googleauthor | Keum Ji Jung | - |
dc.contributor.googleauthor | Bing Li,corresponding | - |
dc.contributor.googleauthor | Qingyu Xiucorresponding | - |
dc.identifier.doi | 10.1186/1741-7015-12-61 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03580 | - |
dc.contributor.localId | A03965 | - |
dc.relation.journalcode | J00364 | - |
dc.identifier.eissn | 1741-7015 | - |
dc.identifier.pmid | 24722122 | - |
dc.subject.keyword | Body mass index | - |
dc.subject.keyword | Obesity | - |
dc.subject.keyword | Pneumonia | - |
dc.subject.keyword | Dose–response relationship | - |
dc.subject.keyword | Meta-analysis | - |
dc.contributor.alternativeName | Jung, Keum Ji | - |
dc.contributor.alternativeName | Jee, Sun Ha | - |
dc.contributor.affiliatedAuthor | Jung, Keum Ji | - |
dc.contributor.affiliatedAuthor | Jee, Sun Ha | - |
dc.citation.volume | 12 | - |
dc.citation.startPage | 61 | - |
dc.identifier.bibliographicCitation | BMC MEDICINE, Vol.12 : 61, 2014 | - |
dc.identifier.rimsid | 54959 | - |
dc.type.rims | ART | - |
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