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Analysis of rheumatoid factor according to various hepatitis B virus infectious statuses
DC Field | Value | Language |
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dc.contributor.author | 박용범 | - |
dc.contributor.author | 이수곤 | - |
dc.date.accessioned | 2015-12-28T11:09:23Z | - |
dc.date.available | 2015-12-28T11:09:23Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0392-856X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138816 | - |
dc.description.abstract | OBJECTIVES: Rheumatoid factor (RF) can be seen in hepatitis B virus (HBV) infection. We investigated RF positive rates according to various HBV infectious statuses and vaccination, and the relationship between RF titers and serum HBV DNA levels. METHODS: We examined 13,670 individuals who visited the Severance Hospital in Seoul, Korea, for a routine health check-up, and obtained serum samples from all individuals. RESULTS: RF was positive in 3.5% of all subjects, and HBsAg was positive in 4.3%. HBsAg was positive in 21.7% of all RF positive subjects. RF was positive in 17.5% of the HBsAg positive group, while it was positive in 2.9% of the HBsAg negative group (p<0.001). The RF positive rate was increased in positive HBsAg, female sex, and older age. The RF positive rate was lower in those who had anti-HBs after HBV vaccination than in HBsAg positive subjects (2.7% vs. 17.5%, p<0.001). Among the RF positive patients, the RF titer in HBsAg positive patients were higher than that in HBsAg negative patients (159.7±217.1IU/mL vs. 83.0±179.2 IU/mL, p=0.001). The load of HBV DNA may be closely correlated with RF titer in patients with chronic hepatitis B (r=0.508, p=0.005). CONCLUSIONS: Persistent HBV infection is an important cause for the positive RF in HBV endemic areas. Hepatitis B viral load is associated with RF titer. HBV vaccination may reduce the risk of RF formation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 168~173 | - |
dc.relation.isPartOf | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | DNA, Viral/blood* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hepatitis B*/epidemiology | - |
dc.subject.MESH | Hepatitis B*/immunology | - |
dc.subject.MESH | Hepatitis B*/physiopathology | - |
dc.subject.MESH | Hepatitis B Antibodies/blood | - |
dc.subject.MESH | Hepatitis B Surface Antigens/blood | - |
dc.subject.MESH | Hepatitis B virus*/genetics | - |
dc.subject.MESH | Hepatitis B virus*/immunology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Patient Acuity | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Rheumatoid Factor*/analysis | - |
dc.subject.MESH | Rheumatoid Factor*/blood | - |
dc.subject.MESH | Sex Factors | - |
dc.subject.MESH | Statistics as Topic | - |
dc.subject.MESH | Viral Load | - |
dc.title | Analysis of rheumatoid factor according to various hepatitis B virus infectious statuses | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | S T Choi | - |
dc.contributor.googleauthor | H W Lee | - |
dc.contributor.googleauthor | J S Song | - |
dc.contributor.googleauthor | S K Lee | - |
dc.contributor.googleauthor | Y B Park | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01579 | - |
dc.contributor.localId | A02889 | - |
dc.relation.journalcode | J00555 | - |
dc.identifier.eissn | 1593-098X | - |
dc.identifier.pmid | 24143967 | - |
dc.identifier.url | http://www.clinexprheumatol.org/abstract.asp?a=7153 | - |
dc.contributor.alternativeName | Park, Yong Beom | - |
dc.contributor.alternativeName | Lee, Soo Kon | - |
dc.contributor.affiliatedAuthor | Park, Yong Beom | - |
dc.contributor.affiliatedAuthor | Lee, Soo Kon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 32 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 168 | - |
dc.citation.endPage | 173 | - |
dc.identifier.bibliographicCitation | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, Vol.32(2) : 168-173, 2014 | - |
dc.identifier.rimsid | 54939 | - |
dc.type.rims | ART | - |
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