Cited 41 times in
Model for assessing cardiovascular risk in a Korean population
DC Field | Value | Language |
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dc.contributor.author | 김현창 | - |
dc.date.accessioned | 2015-12-28T11:06:00Z | - |
dc.date.available | 2015-12-28T11:06:00Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1941-7713 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138691 | - |
dc.description.abstract | BACKGROUND: A model for predicting cardiovascular disease in Asian populations is limited. METHODS AND RESULTS: In total, 57 393 consecutive asymptomatic Korean individuals aged 30 to 80 years without a prior history of cardiovascular disease who underwent a general health examination were enrolled. Subjects were randomly classified into the train (n=45 914) and validation (n=11 479) cohorts. Thirty-one possible risk factors were assessed. The cardiovascular event was a composite of cardiovascular death, myocardial infarction, and stroke. In the train cohort, the C-index (95% confidence interval) and Akaike Information Criterion were used to develop the best-fitting prediction model. In the validation cohort, the predicted versus the observed cardiovascular event rates were compared by the C-index and Nam and D'Agostino χ(2) statistics. During a median follow-up period of 3.1 (interquartile range, 1.9-4.3) years, 458 subjects had 474 cardiovascular events. In the train cohort, the best-fitting model consisted of age, diabetes mellitus, hypertension, current smoking, family history of coronary heart disease, white blood cell, creatinine, glycohemoglobin, atrial fibrillation, blood pressure, and cholesterol (C-index =0.757 [0.726-0.788] and Akaike Information Criterion =7207). When this model was tested in the validation cohort, it performed well in terms of discrimination and calibration abilities (C-index=0.760 [0.693-0.828] and Nam and D'Agostino χ(2) statistic =0.001 for 3 years; C-index=0.782 [0.719-0.846] and Nam and D'Agostino χ(2) statistic=1.037 for 5 years). CONCLUSIONS: A risk model based on traditional clinical and biomarkers has a feasible model performance in predicting cardiovascular events in an asymptomatic Korean population. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 944~951 | - |
dc.relation.isPartOf | CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Cardiovascular Diseases/epidemiology* | - |
dc.subject.MESH | Feasibility Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Morbidity/trends | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Assessment/methods* | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Model for assessing cardiovascular risk in a Korean population | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학) | - |
dc.contributor.googleauthor | Gyung Min Park | - |
dc.contributor.googleauthor | Seungbong Han | - |
dc.contributor.googleauthor | Seon Ha Kim | - |
dc.contributor.googleauthor | Min Woo Jo | - |
dc.contributor.googleauthor | Sung Ho Her | - |
dc.contributor.googleauthor | Jung Bok Lee | - |
dc.contributor.googleauthor | Moo Song Lee | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.contributor.googleauthor | Jung Min Ahn | - |
dc.contributor.googleauthor | Seung Whan Lee | - |
dc.contributor.googleauthor | Young Hak Kim | - |
dc.contributor.googleauthor | Beom Jun Kim | - |
dc.contributor.googleauthor | Jung Min Koh | - |
dc.contributor.googleauthor | Hong Kyu Kim | - |
dc.contributor.googleauthor | Jaewon Choe | - |
dc.contributor.googleauthor | Seong Wook Park | - |
dc.contributor.googleauthor | Seung Jung Park | - |
dc.identifier.doi | 10.1161/CIRCOUTCOMES.114.001305 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01142 | - |
dc.relation.journalcode | J00536 | - |
dc.identifier.eissn | 1941-7705 | - |
dc.identifier.pmid | 25351481 | - |
dc.identifier.url | http://circoutcomes.ahajournals.org/content/7/6/944.abstract | - |
dc.subject.keyword | cardiovascular diseases | - |
dc.subject.keyword | coronary disease | - |
dc.subject.keyword | prevention and control | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | Kim, Hyeon Chang | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 7 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 944 | - |
dc.citation.endPage | 951 | - |
dc.identifier.bibliographicCitation | CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, Vol.7(6) : 944-951, 2014 | - |
dc.identifier.rimsid | 57347 | - |
dc.type.rims | ART | - |
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