Cited 19 times in
Highly fluorescent conjugated polyelectrolyte for protein sensing and cell-compatible chemosensing applications
DC Field | Value | Language |
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dc.contributor.author | 김한수 | - |
dc.contributor.author | 김현옥 | - |
dc.contributor.author | 허준석 | - |
dc.date.accessioned | 2015-12-28T11:05:26Z | - |
dc.date.available | 2015-12-28T11:05:26Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138671 | - |
dc.description.abstract | Using a highly fluorescent, water-soluble polymer derived from a triazine-bridged copolymer (DTMSPV), we explored the tunable fluorescence properties of the water-soluble DTMSPV by solvent polarity to function as a fluorescence sensory probe for protein sensing. The green-blue fluorescence from DTMSPV was significantly enhanced in the presence of bovine serum albumin through hydrophobic interactions. Meanwhile, complete quenching of the fluorescence from DTMSPV occurred in the presence of hemoglobin through iron complexation with the polyelectrolyte. In addition, the DTMSPVs were highly fluorescent and permeated into living mesenchymal stem cells (MSCs), enabling effective imaging of the MSCs. This permeation into stem cells is crucial to the detection of Al(3+) in living MSCs. The interaction between the triazine units in DTMSPV with the Al(3+) ions allows for the detection of Al(3+) in living cells. Thus, a strong fluorescence from living MSCs pretreated with DTMSPV was quenched as a function of the Al(3+) concentration, confirming that DTMSPV is a cell-permeable fluorescent polymer that can function as a versatile probe to detect Al(3+) in living cells. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 3305~3311 | - |
dc.relation.isPartOf | ACS APPLIED MATERIALS & INTERFACES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aluminum/analysis* | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cattle | - |
dc.subject.MESH | Electrolytes/chemistry* | - |
dc.subject.MESH | Fluorescent Dyes/chemistry* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Mesenchymal Stromal Cells/chemistry* | - |
dc.subject.MESH | Mesenchymal Stromal Cells/cytology* | - |
dc.subject.MESH | Proteins/chemistry* | - |
dc.subject.MESH | Spectrometry, Fluorescence | - |
dc.subject.MESH | Swine | - |
dc.title | Highly fluorescent conjugated polyelectrolyte for protein sensing and cell-compatible chemosensing applications | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Jungmok You | - |
dc.contributor.googleauthor | Teahoon Park | - |
dc.contributor.googleauthor | Jeonghun Kim | - |
dc.contributor.googleauthor | June Seok Heo | - |
dc.contributor.googleauthor | Han-Soo Kim | - |
dc.contributor.googleauthor | Hyun Ok Kim | - |
dc.contributor.googleauthor | Eunkyoung Kim | - |
dc.identifier.doi | 10.1021/am500269t | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01100 | - |
dc.contributor.localId | A01122 | - |
dc.contributor.localId | A04367 | - |
dc.relation.journalcode | J00004 | - |
dc.identifier.eissn | 1944-8252 | - |
dc.identifier.pmid | 24527754 | - |
dc.identifier.url | http://pubs.acs.org/doi/abs/10.1021/am500269t | - |
dc.subject.keyword | cell imaging | - |
dc.subject.keyword | chemosensing | - |
dc.subject.keyword | conjugated polymer | - |
dc.subject.keyword | protein sensor | - |
dc.subject.keyword | water-soluble polymer | - |
dc.contributor.alternativeName | Kim, Han Soo | - |
dc.contributor.alternativeName | Kim, Hyun Ok | - |
dc.contributor.alternativeName | Heo, June Seok | - |
dc.contributor.affiliatedAuthor | Kim, Han Soo | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Ok | - |
dc.contributor.affiliatedAuthor | Heo, June Seok | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 6 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 3305 | - |
dc.citation.endPage | 3311 | - |
dc.identifier.bibliographicCitation | ACS APPLIED MATERIALS & INTERFACES, Vol.6(5) : 3305-3311, 2014 | - |
dc.identifier.rimsid | 46125 | - |
dc.type.rims | ART | - |
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