Cited 50 times in
Clinical characteristics and outcomes of hematogenous vertebral osteomyelitis caused by gram-negative bacteria.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 석경수 | - |
dc.date.accessioned | 2015-12-28T11:01:43Z | - |
dc.date.available | 2015-12-28T11:01:43Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0163-4453 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138538 | - |
dc.description.abstract | OBJECTIVE: To evaluate the clinical characteristics and outcomes of patients with hematogenous vertebral osteomyelitis (HVO) caused by gram-negative bacteria (GNB). METHODS: We conducted a retrospective chart review of adult patients with HVO from three tertiary-care hospitals over a 7-year period. RESULTS: Of the 313 microbiologically diagnosed HVO cases, GNB was responsible for 65 (20.8%) cases. Compared with patients with MSSA HVO, patients with GNB HVO were more likely to be female (P = 0.03) and have diabetes (P = 0.03), but less likely to have epidural abscess (P = 0.02) and paravertebral abscess (P = 0.003). Clinical outcomes were similar between the GNB and MSSA groups, including in-hospital mortality (4.6% vs. 7.8%; P = 0.53), recurrence (9.7% vs. 4.3%; P = 0.20), and sequelae (31.7% vs. 32.2%; P = 0.95). Among GNB-infected patients, recurrence rates differed according to the total duration of antibiotic treatment: 40.0% (4-6 weeks), 33.3% (6-8 weeks), and 2.1% (≥ 8 weeks) (P = 0.002). CONCLUSIONS: GNB HVO was responsible for 20.8% of adult cases of HVO. Despite some differences in clinical and radiological presentation, clinical outcomes were similar between GNB and MSSA HVO. Antibiotic therapy for ≥ 8 weeks may benefit patients with GNB HVO. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 42~50 | - |
dc.relation.isPartOf | JOURNAL OF INFECTION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anti-Bacterial Agents/therapeutic use* | - |
dc.subject.MESH | Bacteremia/complications* | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gram-Negative Bacterial Infections/drug therapy | - |
dc.subject.MESH | Gram-Negative Bacterial Infections/pathology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Osteomyelitis/drug therapy | - |
dc.subject.MESH | Osteomyelitis/pathology* | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Spondylitis/drug therapy | - |
dc.subject.MESH | Spondylitis/pathology* | - |
dc.subject.MESH | Staphylococcal Infections/drug therapy | - |
dc.subject.MESH | Staphylococcal Infections/pathology | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Tertiary Care Centers | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Young Adult | - |
dc.title | Clinical characteristics and outcomes of hematogenous vertebral osteomyelitis caused by gram-negative bacteria. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Orthopedic Surgery (정형외과학) | - |
dc.contributor.googleauthor | Ki Ho Park | - |
dc.contributor.googleauthor | Oh Hyun Cho | - |
dc.contributor.googleauthor | Myounghwa Jung | - |
dc.contributor.googleauthor | Kyung Soo Suk | - |
dc.contributor.googleauthor | Jung Hee Lee | - |
dc.contributor.googleauthor | Ji Seon Park | - |
dc.contributor.googleauthor | Kyung Nam Ryu | - |
dc.contributor.googleauthor | Sung Han Kim | - |
dc.contributor.googleauthor | Sang Oh Lee | - |
dc.contributor.googleauthor | Sang Ho Choi | - |
dc.contributor.googleauthor | In Gyu Bae | - |
dc.contributor.googleauthor | Yang Soo Kim | - |
dc.contributor.googleauthor | Jun Hee Woo | - |
dc.contributor.googleauthor | Mi Suk Lee | - |
dc.identifier.doi | 10.1016/j.jinf.2014.02.009 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01926 | - |
dc.relation.journalcode | J01452 | - |
dc.identifier.eissn | 1532-2742 | - |
dc.identifier.pmid | 24561018 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0163445314000450 | - |
dc.subject.keyword | Gram-negative bacteria | - |
dc.subject.keyword | Outcome | - |
dc.subject.keyword | Spondylitis | - |
dc.subject.keyword | Spondylodiscitis | - |
dc.subject.keyword | Vertebral osteomyelitis | - |
dc.contributor.alternativeName | Suk, Kyung Soo | - |
dc.contributor.affiliatedAuthor | Suk, Kyung Soo | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 69 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 42 | - |
dc.citation.endPage | 50 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INFECTION, Vol.69(1) : 42-50, 2014 | - |
dc.identifier.rimsid | 38368 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.