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Impact of atherosclerosis detection by carotid ultrasound on physician behavior and risk-factor management in asymptomatic hypertensive subjects.

DC Field Value Language
dc.contributor.author박승우-
dc.contributor.author송기준-
dc.contributor.author장혁재-
dc.contributor.author홍그루-
dc.contributor.author홍성진-
dc.date.accessioned2015-12-28T10:59:20Z-
dc.date.available2015-12-28T10:59:20Z-
dc.date.issued2014-
dc.identifier.issn0160-9289-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/138454-
dc.description.abstractBACKGROUND: There are limited data regarding the impact of atherosclerosis detection by carotid ultrasound (CUS) on physician prevention efforts and risk-factor management for cardiovascular disease. HYPOTHESIS: Atherosclerosis detection by CUS in asymptomatic hypertensive patients would lead to physician prevention efforts, including target low-density lipoprotein cholesterol (LDL-C) level and prescription. Also, it may improve risk-factor management. METHODS: A total of 347 asymptomatic hypertensive subjects (age 61 ± 8 years, 189 men) were prospectively recruited from 22 hospitals. Prior to CUS, physicians were surveyed regarding target LDL-C level. After CUS, patients were classified into positive CUS (n = 182) and negative CUS (n = 165) groups based on CUS results. Physicians were resurveyed to assess whether the initial target LDL-C goals were changed. At 6 months, cardiovascular risk-factor modification status was reassessed. RESULTS: The proportion of lowered target LDL-C levels was significantly larger in the positive CUS group than in the negative CUS group (52% vs 23%, P < 0.001). These results were observed even in subjects who had low and moderate risk according to National Cholesterol Education Program-Adult Treatment Panel III guidelines. Lipid-lowering agents were similarly added or switched to another class in both groups (7% in the positive CUS group vs 11% in the negative CUS group, P = 0.153). LDL-C was significantly decreased in the positive CUS group (Δ = -24 ± 38 mg/dL, P < 0.001), whereas it was not significantly decreased in the negative CUS group (Δ = -6 ± 31 mg/dL, P = 0.105). CONCLUSIONS: Atherosclerosis detection by CUS lowered physicians' target LDL-C level and improved cardiovascular risk management in terms of LDL-C reduction.-
dc.description.statementOfResponsibilityopen-
dc.format.extent91~96-
dc.relation.isPartOfCLINICAL CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAsymptomatic Diseases-
dc.subject.MESHAttitude of Health Personnel*-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHCarotid Arteries/diagnostic imaging*-
dc.subject.MESHCarotid Artery Diseases/blood-
dc.subject.MESHCarotid Artery Diseases/diagnostic imaging-
dc.subject.MESHCarotid Artery Diseases/drug therapy*-
dc.subject.MESHCarotid Artery Diseases/epidemiology-
dc.subject.MESHCarotid Intima-Media Thickness*-
dc.subject.MESHCholesterol, LDL/blood-
dc.subject.MESHFemale-
dc.subject.MESHHealth Knowledge, Attitudes, Practice*-
dc.subject.MESHHumans-
dc.subject.MESHHypertension/diagnosis-
dc.subject.MESHHypertension/drug therapy*-
dc.subject.MESHHypertension/epidemiology-
dc.subject.MESHHypolipidemic Agents/therapeutic use*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPhysicians/psychology*-
dc.subject.MESHPractice Patterns, Physicians'*-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHProspective Studies-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Assessment-
dc.subject.MESHRisk Factors-
dc.titleImpact of atherosclerosis detection by carotid ultrasound on physician behavior and risk-factor management in asymptomatic hypertensive subjects.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSung Jin Hong-
dc.contributor.googleauthorHyuk Jae Chang-
dc.contributor.googleauthorKijun Song-
dc.contributor.googleauthorGeu Ru Hong-
dc.contributor.googleauthorSeung Woo Park-
dc.contributor.googleauthorHyun Jae Kang-
dc.contributor.googleauthorEung Ju Kim-
dc.contributor.googleauthorDong Soo Kim-
dc.contributor.googleauthorMyung Ho Jeong-
dc.identifier.doi10.1002/clc.22220-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01551-
dc.contributor.localIdA02016-
dc.contributor.localIdA03490-
dc.contributor.localIdA04386-
dc.contributor.localIdA04403-
dc.relation.journalcodeJ00565-
dc.identifier.eissn1932-8737-
dc.identifier.pmid24193449-
dc.contributor.alternativeNamePark, Seung Woo-
dc.contributor.alternativeNameSong, Ki Jun-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.alternativeNameHong, Sung Jin-
dc.contributor.affiliatedAuthorPark, Seung Woo-
dc.contributor.affiliatedAuthorSong, Ki Jun-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.contributor.affiliatedAuthorHong, Sung Jin-
dc.citation.volume37-
dc.citation.number2-
dc.citation.startPage91-
dc.citation.endPage96-
dc.identifier.bibliographicCitationCLINICAL CARDIOLOGY, Vol.37(2) : 91-96, 2014-
dc.identifier.rimsid45322-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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