Cited 12 times in
Urban-rural differences explain the association between serum 25-hydroxyvitamin D level and insulin resistance in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김창오 | - |
dc.contributor.author | 김현창 | - |
dc.contributor.author | 윤영미 | - |
dc.contributor.author | 이유미 | - |
dc.contributor.author | 이은영 | - |
dc.contributor.author | 이주미 | - |
dc.date.accessioned | 2015-12-28T10:58:38Z | - |
dc.date.available | 2015-12-28T10:58:38Z | - |
dc.date.issued | 2014 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138429 | - |
dc.description.abstract | An increasing number of studies report associations between low serum 25-hydroxyvitamin D [25(OH)D] level and insulin resistance; however, whether low vitamin D levels directly contribute to increased insulin resistance is unclear. We investigated the impact of residential area on the association between 25(OH)D and insulin resistance in elderly Koreans. Using data from the Korean Urban Rural Elderly study, we conducted cross-sectional analyses in 1628 participants (505 men and 1123 women). Serum 25(OH)D was analyzed as both continuous and categorized variables. Homeostasis model assessment for insulin resistance (HOMA-IR) was calculated using fasting blood glucose and insulin levels. In men, 25(OH)D level was inversely associated with HOMA-IR (standardized β = -0.133, p < 0.001) after adjustment for age, body mass index, waist circumference, smoking, alcohol intake, exercise, and study year. However, we noted significant urban-rural differences in 25(OH)D level (43.4 versus 65.6 nmol/L; p < 0.001) and HOMA-IR (1.2 versus 0.8 mmol · pmol/L2; p < 0.001). When we additionally adjusted for residential area, the association between 25(OH)D and HOMA-IR was attenuated (standardized β = -0.063, p = 0.115). In women, the association between 25(OH)D and HOMA-IR was not significant before or after adjustment for residential area. Environmental or lifestyle differences in urban and rural areas may largely explain the inverse association between serum 25(OH)D and insulin resistance. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 5806~5818 | - |
dc.relation.isPartOf | NUTRIENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Blood Glucose | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Body Weight | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Insulin/blood | - |
dc.subject.MESH | Insulin Resistance* | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Rural Population* | - |
dc.subject.MESH | Surveys and Questionnaires | - |
dc.subject.MESH | Urban Population* | - |
dc.subject.MESH | Vitamin D/analogs & derivatives* | - |
dc.subject.MESH | Vitamin D/blood | - |
dc.subject.MESH | Waist Circumference | - |
dc.title | Urban-rural differences explain the association between serum 25-hydroxyvitamin D level and insulin resistance in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Biostatistics (의학통계학) | - |
dc.contributor.googleauthor | Bo Mi Song | - |
dc.contributor.googleauthor | Yumie Rhee | - |
dc.contributor.googleauthor | Chang Oh Kim | - |
dc.contributor.googleauthor | Yoosik Youm | - |
dc.contributor.googleauthor | Kyoung Min Kim | - |
dc.contributor.googleauthor | Eun Young Lee | - |
dc.contributor.googleauthor | Ju-Mi Lee | - |
dc.contributor.googleauthor | Young Mi Yoon | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.identifier.doi | 10.3390/nu6125806 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01044 | - |
dc.contributor.localId | A01142 | - |
dc.contributor.localId | A02577 | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03157 | - |
dc.contributor.localId | A03042 | - |
dc.relation.journalcode | J02396 | - |
dc.identifier.eissn | 2072-6643 | - |
dc.identifier.pmid | 25514561 | - |
dc.subject.keyword | vitamin D | - |
dc.subject.keyword | insulin resistance | - |
dc.subject.keyword | elderly | - |
dc.subject.keyword | Korean | - |
dc.subject.keyword | residential area | - |
dc.contributor.alternativeName | Kim, Chang Oh | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.alternativeName | Yun, Young Mi | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lee, Eun Young | - |
dc.contributor.alternativeName | Lee, Ju Mi | - |
dc.contributor.affiliatedAuthor | Kim, Chang Oh | - |
dc.contributor.affiliatedAuthor | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | Yun, Young Mi | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Lee, Ju Mi | - |
dc.contributor.affiliatedAuthor | Lee, Eun Young | - |
dc.citation.volume | 6 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 5806 | - |
dc.citation.endPage | 5818 | - |
dc.identifier.bibliographicCitation | NUTRIENTS, Vol.6(12) : 5806-5818, 2014 | - |
dc.identifier.rimsid | 49167 | - |
dc.type.rims | ART | - |
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