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Predictors of mortality in cirrhotic patients undergoing extrahepatic surgery: comparison of Child-Turcotte-Pugh and model for end-stage liver disease-based indices

DC FieldValueLanguage
dc.contributor.author노성훈-
dc.contributor.author이우정-
dc.contributor.author김경식-
dc.contributor.author김남규-
dc.contributor.author김충배-
dc.date.accessioned2015-12-28T10:56:24Z-
dc.date.available2015-12-28T10:56:24Z-
dc.date.issued2014-
dc.identifier.issn1445-1433-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/138350-
dc.description.abstractBACKGROUND: Underlying liver cirrhosis is associated with high morbidity and mortality after surgery. Previous studies have reported conflicting results about the value of Child-Turcotte-Pugh (CTP) and model for end-stage liver disease (MELD) scores as predictors of post-operative mortality. This study was designed to compare the capacities of CTP, MELD and MELD-based indices in predicting mortality for patients with liver cirrhosis who underwent elective extrahepatic surgery. METHODS: The medical records of 79 patients with liver cirrhosis who underwent elective extrahepatic surgery under general anaesthesia from December 2000 to December 2009 were reviewed retrospectively. RESULTS: The median follow-up period was 21 months, and the mortality rate was 24.1% (n = 19). Among the 19 mortalities, nine (11.4%) occurred while the patient was hospitalized after surgery. Intraoperative transfusion amount (≥700 mL; odds ratio 6.294, P = 0.004) and the integrated MELD score (≥34; odds ratio 6.654, P = 0.007) were significantly correlated with post-operative mortality. CTP score (hazard ratio 1.575, P = 0.012) was significantly correlated with overall mortality. CONCLUSIONS: Integrated MELD may be a more accurate predictor of operative mortality in cirrhotic patients undergoing extrahepatic surgery than CTP and other MELD-Na based indices. However, overall mortality may be reflected more accurately by CTP score. Further large-scale study will be needed to validate this result.-
dc.description.statementOfResponsibilityopen-
dc.format.extent832~836-
dc.relation.isPartOfANZ JOURNAL OF SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHElective Surgical Procedures/methods*-
dc.subject.MESHEnd Stage Liver Disease/diagnosis*-
dc.subject.MESHEnd Stage Liver Disease/etiology-
dc.subject.MESHEnd Stage Liver Disease/mortality-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHealth Status Indicators*-
dc.subject.MESHHumans-
dc.subject.MESHIntraoperative Period-
dc.subject.MESHLiver Cirrhosis/complications-
dc.subject.MESHLiver Cirrhosis/mortality*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostoperative Period-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPrognosis-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment/methods*-
dc.subject.MESHRisk Factors-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHSurvival Rate/trends-
dc.subject.MESHYoung Adult-
dc.titlePredictors of mortality in cirrhotic patients undergoing extrahepatic surgery: comparison of Child-Turcotte-Pugh and model for end-stage liver disease-based indices-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorDong Hyun Kim-
dc.contributor.googleauthorSung Hoon Kim-
dc.contributor.googleauthorKyung Sik Kim-
dc.contributor.googleauthorWoo Jung Lee-
dc.contributor.googleauthorNam Kyu Kim-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorChoong Bai Kim-
dc.identifier.doi10.1111/ans.12198-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02993-
dc.contributor.localIdA01281-
dc.contributor.localIdA00299-
dc.contributor.localIdA00353-
dc.contributor.localIdA01063-
dc.relation.journalcodeJ00193-
dc.identifier.eissn1445-2197-
dc.identifier.pmid23647879-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/ans.12198/abstract-
dc.subject.keywordextrahepatic surgery-
dc.subject.keywordliver cirrhosis-
dc.subject.keywordmortality-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameLee, Woo Jung-
dc.contributor.alternativeNameKim, Kyung Sik-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.alternativeNameKim, Choong Bai-
dc.contributor.affiliatedAuthorLee, Woo Jung-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorKim, Kyung Sik-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.contributor.affiliatedAuthorKim, Choong Bai-
dc.rights.accessRightsfree-
dc.citation.volume84-
dc.citation.number11-
dc.citation.startPage832-
dc.citation.endPage836-
dc.identifier.bibliographicCitationANZ JOURNAL OF SURGERY, Vol.84(11) : 832-836, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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