Cited 0 times in
Mouse Models of Gastric Carcinogenesis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남기택 | - |
dc.contributor.author | 유성숙 | - |
dc.date.accessioned | 2015-12-28T10:55:22Z | - |
dc.date.available | 2015-12-28T10:55:22Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 2093-582X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138313 | - |
dc.description.abstract | Gastric cancer is one of the most common cancers in the world. Animal models have been used to elucidate the details of the molecular mechanisms of various cancers. However, most inbred strains of mice have resistance to gastric carcinogenesis. Helicobacter infection and carcinogen treatment have been used to establish mouse models that exhibit phenotypes similar to those of human gastric cancer. A large number of transgenic and knockout mouse models of gastric cancer have been developed using genetic engineering. A combination of carcinogens and gene manipulation has been applied to facilitate development of advanced gastric cancer; however, it is rare for mouse models of gastric cancer to show aggressive, metastatic phenotypes required for preclinical studies. Here, we review current mouse models of gastric carcinogenesis and provide our perspectives on future developments in this field. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | JOURNAL OF GASTRIC CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Mouse Models of Gastric Carcinogenesis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Life Science (의생명과학부) | - |
dc.contributor.googleauthor | Sungsook Yu | - |
dc.contributor.googleauthor | Mijeong Yang | - |
dc.contributor.googleauthor | Ki Taek Nam | - |
dc.identifier.doi | 10.5230/jgc.2014.14.2.67. | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01243 | - |
dc.contributor.localId | A02473 | - |
dc.relation.journalcode | J01415 | - |
dc.identifier.eissn | 2093-5641 | - |
dc.identifier.pmid | 25061535 | - |
dc.subject.keyword | Helicobacter infections | - |
dc.subject.keyword | Mouse model | - |
dc.subject.keyword | Stomach neopla는 | - |
dc.contributor.alternativeName | Nam, Ki Taek | - |
dc.contributor.alternativeName | Yu, Sungsook | - |
dc.contributor.affiliatedAuthor | Nam, Ki Taek | - |
dc.contributor.affiliatedAuthor | Yu, Sungsook | - |
dc.citation.volume | 14 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 67 | - |
dc.citation.endPage | 86 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTRIC CANCER, Vol.14(2) : 67-86, 2014 | - |
dc.identifier.rimsid | 52799 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.