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Abstract

[한글]

SIGNIFICANCE OF LIVER SCAN IN INTRAHEPATIC STONE

Il Saing Choi, M.D.

Dept. of Medical Science, the Graduate School, Yonsei University

(Directed by Professor Eung Suk Chai)

Intrahepatic stone is a disease characterized by recurrent biliary colic and

higher incidence in Asians than in Cauoassians. There are various diagnostic

methods for intrahepatic stone, but none are entirely satisfactory except surgical

exploration. Since liver scan was introduced by Stirrett, et al, in 1953, it has

been used in the diagnosis of liver diseases such as space occupying lesions,

cirrhosis of liver and others.

The present study was done to assess the diagnostic value of liver scan in

intrahepatic stone. Liver scan was performed on 15 of 28 cases of intrahepatic

stone confirmed by operation at Severance Hospital, Yonsei University College of

Medicine, from January 1969 to June 1971, and was compared with those in 17 among

94 cases or other biliary stone.

The results were as follows;

1. The incidence of intrahepatic stone in hepatobiliary stone was 22.9%, the

ratio of male to female was 1:1.3 and the range of age was 23 to 73 with the mean

age of 45.

2. In liver function tests, there were significant increases in the values of

total bilirubin, total cholesterol and alkaline phosphatase in both intrahepatic

stone and common bile duct stone, while serum albumin was low(2.9±0.5 gm%) in

intrahepatic stone only.

3. In the liver scan, the characteristic findings of intrahepatic stone were cold

areas, mottling and decreased uptake, whereas in other biliary stone, the findings

were almost normal. The size of cold and mottling areas varied from a few

millimeter to a centimeter, and their location coincided with the site of stones at

operation. In cases of intrahepatic stone, liver scan showed decrease liver uptake

and no increased spleen uptake in contrast to the cases of cirrhosis of liver.

[영문]

Intrahepatic stone is a disease characterized by recurrent biliary colic and higher incidence in Asians than in Cauoassians. There are various diagnostic methods for intrahepatic stone, but none are entirely satisfactory except surgical exploration. Since liver scan was introduced by Stirrett, et al, in 1953, it has

been used in the diagnosis of liver diseases such as space occupying lesions, cirrhosis of liver and others.

The present study was done to assess the diagnostic value of liver scan in intrahepatic stone. Liver scan was performed on 15 of 28 cases of intrahepatic stone confirmed by operation at Severance Hospital, Yonsei University College of Medicine, from January 1969 to June 1971, and was compared with those in 17 among 94 cases or other biliary stone.

The results were as follows;

1. The incidence of intrahepatic stone in hepatobiliary stone was 22.9%, the ratio of male to female was 1:1.3 and the range of age was 23 to 73 with the mean age of 45.

2. In liver function tests, there were significant increases in the values of total bilirubin, total cholesterol and alkaline phosphatase in both intrahepatic stone and common bile duct stone, while serum albumin was low(2.9±0.5 gm%) in intrahepatic stone only.

3. In the liver scan, the characteristic findings of intrahepatic stone were cold areas, mottling and decreased uptake, whereas in other biliary stone, the findings

were almost normal. The size of cold and mottling areas varied from a few millimeter to a centimeter, and their location coincided with the site of stones at operation. In cases of intrahepatic stone, liver scan showed decrease liver uptake

and no increased spleen uptake in contrast to the cases of cirrhosis of liver.