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Plant stanol esters in low-fat yogurt reduces total and low-density lipoprotein cholesterol and low-density lipoprotein oxidation in normocholesterolemic and mildly hypercholesterolemic subjects
DC Field | Value | Language |
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dc.contributor.author | 장양수 | - |
dc.date.accessioned | 2015-08-26T16:36:49Z | - |
dc.date.available | 2015-08-26T16:36:49Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0271-5317 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/114790 | - |
dc.description.abstract | We examined the effects of plant stanol ester contained in low-fat yogurt on serum lipids and low-density lipoprotein (LDL) oxidation in Korean young adults with normocholesterolemia and mild hypercholesterolemia. After screening tests (fasting total cholesterol, 174 to 251 mg/dL; and fasting triacylglycerols, <266 mg/dL), 51 subjects (28.7 ± 0.7 years, 22.6 ± 0.4 kg/m2) were included in the study and randomly assigned to a group receiving yogurt with either a plant stanol ester or a placebo. Four weeks' intake of plant stanol (2 g/d) as its fatty acid ester lowered total and LDL cholesterol levels by almost 6% and 10%, respectively, without affecting high-density lipoprotein cholesterol and triacylglycerol concentrations. Plasma oxidized LDL was also reduced by 5.4% in the test group. Serum β-carotene and retinol were unchanged in both groups; however, lipid-corrected serum α-tocopherol was significantly increased in the test group (P < .05) We conclude that plant stanol ester contained in low-fat yogurt may be effective in reducing total and LDL cholesterol and oxidized LDL level in a habitual diet without restriction of fat and cholesterol intake. Foods containing plant sterols or stanols might be a useful tool for normocholesterolemic and mildly hypercholesterolemic individuals to prevent more severe hypercholesterolemia and cardiovascular disease. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 743~753 | - |
dc.relation.isPartOf | NUTRITION RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Plant stanol ester | - |
dc.subject.MESH | Serum lipids | - |
dc.subject.MESH | LDL oxidation | - |
dc.subject.MESH | Young adult | - |
dc.subject.MESH | Normocholesterolemia and mild hypercholesterolemia | - |
dc.title | Plant stanol esters in low-fat yogurt reduces total and low-density lipoprotein cholesterol and low-density lipoprotein oxidation in normocholesterolemic and mildly hypercholesterolemic subjects | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Yae Jung Hyun | - |
dc.contributor.googleauthor | Oh Yoen Kim | - |
dc.contributor.googleauthor | Pia Salo | - |
dc.contributor.googleauthor | Lippo Liponkoski | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Jong Ho Lee | - |
dc.contributor.googleauthor | Joo Byung Kang | - |
dc.identifier.doi | 10.1016/j.nutres.2005.08.004 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03448 | - |
dc.relation.journalcode | J02401 | - |
dc.identifier.eissn | 1879-0739 | - |
dc.identifier.pmid | 10.1016/j.nutres.2005.08.004 | - |
dc.identifier.url | http://www.nrjournal.com/article/S0271-5317(05)00149-1/abstract | - |
dc.subject.keyword | Plant stanol ester | - |
dc.subject.keyword | Serum lipids | - |
dc.subject.keyword | LDL oxidation | - |
dc.subject.keyword | Young adult | - |
dc.subject.keyword | Normocholesterolemia and mild hypercholesterolemia | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 25 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 743 | - |
dc.citation.endPage | 753 | - |
dc.identifier.bibliographicCitation | NUTRITION RESEARCH, Vol.25(8) : 743-753, 2005 | - |
dc.identifier.rimsid | 38476 | - |
dc.type.rims | ART | - |
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