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Basaloid carcinoma of the lung: a really dismal histologic variant?

DC FieldValueLanguage
dc.contributor.author김길동-
dc.contributor.author김대준-
dc.contributor.author신동환-
dc.contributor.author정경영-
dc.date.accessioned2015-07-15T17:17:37Z-
dc.date.available2015-07-15T17:17:37Z-
dc.date.issued2003-
dc.identifier.issn0003-4975-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/114618-
dc.description.abstractBACKGROUND: Basaloid carcinoma of the lung has been reported as an uncommon and highly aggressive form of nonsmall cell lung cancers. Even in stage I and II of basaloid carcinoma, a 5-year survival rate of only 15% has been reported and it has been suggested that different treatment modalities for basaloid carcinoma should be considered. The aim of this study was to determine the prognostic implications of a basaloid carcinoma of the lung. METHODS: This study included a series of 291 surgically resected lung tumors, which were originally diagnosed as a poorly or undifferentiated carcinoma, a small cell carcinoma, or an atypical carcinoid. Of these, 35 basaloid carcinoma patients were identified and compared with 167 poorly differentiated squamous cell carcinoma (PDSC) patients in terms of the preoperative clinical data, the procedure performed, and the survival outcome. RESULTS: The overall incidence of basaloid carcinoma was 4.8%. The actuarial 5-year survival rate was 40.6% in patients with PDSC and 36.5% in those with basaloid carcinoma (p = 0.86). In stage I and II patients, the actuarial 5-year survival rate was 53.9% in the PDSC group and 57.2% in the basaloid group (p = 0.97). There were no differences in the recurrence rate and the relapse pattern (p = 0.584). Cox's proportional hazards model revealed that an age equal to 60 years old (hazard ratio 2.179, p = 0.000) and an advanced stage (hazard ratio 2.264, p = 0.000) were the risk factors for postoperative survival in both groups. CONCLUSIONS: Basaloid carcinoma of the lung does not have a worse prognosis than the other nonsmall cell lung cancers. Although it is obvious that a basaloid carcinoma is a unique histologic entity, it does not require a different treatment modality due to the similar clinical behavior with other nonsmall cell lung cancers.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1833~1837-
dc.relation.isPartOfANNALS OF THORACIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCarcinoma, Basal Cell*/diagnosis-
dc.subject.MESHCarcinoma, Basal Cell*/mortality-
dc.subject.MESHCarcinoma, Basal Cell*/secondary-
dc.subject.MESHCarcinoma, Basal Cell*/surgery-
dc.subject.MESHCarcinoma, Non-Small-Cell Lung*/diagnosis-
dc.subject.MESHCarcinoma, Non-Small-Cell Lung*/mortality-
dc.subject.MESHCarcinoma, Non-Small-Cell Lung*/surgery-
dc.subject.MESHDiagnosis, Differential-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLung Neoplasms*/diagnosis-
dc.subject.MESHLung Neoplasms*/mortality-
dc.subject.MESHLung Neoplasms*/pathology-
dc.subject.MESHLung Neoplasms*/surgery-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Recurrence, Local-
dc.subject.MESHPrognosis-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurvival Rate-
dc.titleBasaloid carcinoma of the lung: a really dismal histologic variant?-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorDae Joon Kim-
dc.contributor.googleauthorKil Dong Kim-
dc.contributor.googleauthorKyung Young Chung-
dc.contributor.googleauthorJae Y Ro-
dc.contributor.googleauthorDong Hwan Shin-
dc.identifier.doi10.1016/S0003-4975(03)01296-7-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00346-
dc.contributor.localIdA00368-
dc.contributor.localIdA02098-
dc.contributor.localIdA03571-
dc.relation.journalcodeJ00183-
dc.identifier.eissn1552-6259-
dc.identifier.pmid14667594-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0003497503012967-
dc.subject.keyword14667594-
dc.contributor.alternativeNameKim, Kil Dong-
dc.contributor.alternativeNameKim, Dae Joon-
dc.contributor.alternativeNameShin, Dong Hwan-
dc.contributor.alternativeNameChung, Kyung Young-
dc.contributor.affiliatedAuthorKim, Kil Dong-
dc.contributor.affiliatedAuthorKim, Dae Joon-
dc.contributor.affiliatedAuthorShin, Dong Hwan-
dc.contributor.affiliatedAuthorChung, Kyung Young-
dc.rights.accessRightsnot free-
dc.citation.volume76-
dc.citation.number6-
dc.citation.startPage1833-
dc.citation.endPage1837-
dc.identifier.bibliographicCitationANNALS OF THORACIC SURGERY, Vol.76(6) : 1833-1837, 2003-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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