Cited 51 times in
Circulating numbers of endothelial progenitor cells in patients with gastric and breast cancer
DC Field | Value | Language |
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dc.contributor.author | 김현옥 | - |
dc.date.accessioned | 2015-07-15T17:09:52Z | - |
dc.date.available | 2015-07-15T17:09:52Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/114356 | - |
dc.description.abstract | Angiogenic factors like VEGF or G-CSF were reported to mobilize endothelial progenitor cells (EPCs) from the bone marrow. These EPCs were shown to be incorporated in the neovessels of developing tumors. Although the concentrations of angiogenic factors in the peripheral blood were reported to be elevated in cancer patients, the number of circulating EPCs has not been previously investigated. In this study, the number of EPCs circulating in the blood in 16 healthy controls and 71 newly diagnosed cancer patients was examined by a culture assay of peripheral blood mononuclear cells. The number of circulating EPCs was not found to be increased in cancer patients, although the plasma levels of VEGF were elevated. It is suggested that VEGF, at concentrations typical of those observed in the blood of cancer patients, does not mobilize EPCs into the peripheral blood. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 83~88 | - |
dc.relation.isPartOf | CANCER LETTERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Breast Neoplasms/blood supply* | - |
dc.subject.MESH | Endothelial Growth Factors/blood | - |
dc.subject.MESH | Endothelium/cytology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intercellular Signaling Peptides and Proteins/blood | - |
dc.subject.MESH | Lymphokines/blood | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myeloid Progenitor Cells* | - |
dc.subject.MESH | Stomach Neoplasms/blood supply* | - |
dc.subject.MESH | Vascular Endothelial Growth Factor A | - |
dc.subject.MESH | Vascular Endothelial Growth Factors | - |
dc.title | Circulating numbers of endothelial progenitor cells in patients with gastric and breast cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Hyun Kyung Kim | - |
dc.contributor.googleauthor | Kyung Soon Song | - |
dc.contributor.googleauthor | Jae-Moon Bae | - |
dc.contributor.googleauthor | Keun Won Ryu | - |
dc.contributor.googleauthor | Hark Kyun Kim | - |
dc.contributor.googleauthor | Eun Sook Lee | - |
dc.contributor.googleauthor | Dae Ho Lee | - |
dc.contributor.googleauthor | Young-Joon Lee | - |
dc.contributor.googleauthor | Kyoung Rhan Lee | - |
dc.contributor.googleauthor | Jun-Ho Chung | - |
dc.contributor.googleauthor | Hyun Ok Kim | - |
dc.identifier.doi | 10.1016/S0304-3835(03)00268-4 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01122 | - |
dc.relation.journalcode | J00448 | - |
dc.identifier.eissn | 1872-7980 | - |
dc.identifier.pmid | 12893434 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0304383503002684 | - |
dc.subject.keyword | Endothelial progenitor cellsv | - |
dc.subject.keyword | Angiogenic factor | - |
dc.subject.keyword | Mobilization | - |
dc.contributor.alternativeName | Kim, Hyun Ok | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Ok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 198 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 83 | - |
dc.citation.endPage | 88 | - |
dc.identifier.bibliographicCitation | CANCER LETTERS, Vol.198(1) : 83-88, 2003 | - |
dc.identifier.rimsid | 47250 | - |
dc.type.rims | ART | - |
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