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폐구균의 질병양상 및 항균제 내성률의 변화

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dc.contributor.author김동수-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.date.accessioned2015-07-15T17:07:39Z-
dc.date.available2015-07-15T17:07:39Z-
dc.date.issued2003-
dc.identifier.issn1226-3923-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/114281-
dc.description.abstractPurpose : Streptococcus pneumoniae remains a leading cause of meningitis, sepsis, pneumonia, and otitis media in children worldwide. Emergence of drug-resistant organism has substantially complicated the therapy of these infections. This study was conducted to determine the clinical features and changing patterns of antibiotic-resistant rates of Streptococcus pneumoniae. Methods : We have retrospectively examined 306 cases of culture proven patients who were admitted to the Department of Pediatrics, Severance hospital, from the year 1991 to year 2000. The type of culture specimen used, presence of penicillin resistance, characteristics according to various presenting diseases and their prevailing year were also examined. Results : The mean age of cases was 7.9 year and the ratio of male to female was 1.6 : 1. The main age group of pneumococcal infection was under 2 years(42%). Systemic infections associated with pneumococci were sepsis(19.3%) and meningitis(9.5%), while local infections presented as pneumonia(29.2%), otitis media(19.3%), exudative tonsillitis(13.3%), and sinusitis(9.2%) in the order of frequency. Seasonal variation was seen in the incidence of pneumococcal infection: high incidence of infection was seen in Spring(Mar.~Apr; 32%), while the incidence was low during summer(Aug.~Sep.; 6%). Penicillin-resistant rate of pneumococci was steadily on the increase since the year 1991(65%) to year 2000(84%). Conclusion : Antibiotic-resistant pneumococci increased during the past decade. For effective prevention of pneumococcal infections, national survey of pneumococcal infections and expanded use of pneumococcal vaccination would be needed.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfKorean Journal of Pediatric Infectious Diseases (소아감염)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHStreptococcus pneumoniae-
dc.subject.MESHAntibiotic-resistant rates-
dc.subject.MESHChildren-
dc.title폐구균의 질병양상 및 항균제 내성률의 변화-
dc.title.alternativeChanging Patterns of Antibiotic-resistant Rates and Clinical Features in Pneumococcal Infections-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthor장광천-
dc.contributor.googleauthor신경미-
dc.contributor.googleauthor김동수-
dc.contributor.googleauthor이경원-
dc.contributor.googleauthor용동은-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA00405-
dc.relation.journalcodeJ02097-
dc.subject.keywordStreptococcus pneumoniae-
dc.subject.keywordAntibiotic-resistant rates-
dc.subject.keywordChildren-
dc.contributor.alternativeNameKim, Dong Soo-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorKim, Dong Soo-
dc.rights.accessRightsfree-
dc.citation.volume10-
dc.citation.number1-
dc.citation.startPage81-
dc.citation.endPage86-
dc.identifier.bibliographicCitationKorean Journal of Pediatric Infectious Diseases (소아감염), Vol.10(1) : 81-86, 2003-
dc.identifier.rimsid41886-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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