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Effect of staphylococcal enterotoxin B on specific antibody production in children with atopic dermatitis.
DC Field | Value | Language |
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dc.contributor.author | 김규언 | - |
dc.contributor.author | 손명현 | - |
dc.date.accessioned | 2015-07-15T17:06:46Z | - |
dc.date.available | 2015-07-15T17:06:46Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 1088-5412 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/114251 | - |
dc.description.abstract | Exotoxins secreted by Staphylococcus aureus have been identified as a possible trigger factor in atopic dermatitis (AD). We investigated the production and role of circulating antibodies, with specificity to staphylococcal enterotoxin B (SEB), in children with AD compared with those of healthy controls. The children with AD had significantly higher levels of serum SEB-specific immunoglobulin G (IgG; p = 0.0193), IgM (p = 0.011), and IgE (p = 0.0001) than the nonatopic children. The proportions of IgG, IgM, and IgE seropositivity in children with AD were 52.5% (21/40), 62.5% (25/40), and 67.5% (27/40), respectively. The levels of SEB-specific IgE and the severity of AD (p = 0.0004) were compared, but no correlation was seen for IgG or IgM. SEB may be involved in exacerbation of AD. SEB-specific IgE may be an important index of the clinical severity of AD. The SEB-specific IgG or IgM was produced during the exposure to the SEB antigen but may not be protective against SEB in AD. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | ALLERGY AND ASTHMA PROCEEDINGS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Antibody Formation/immunology* | - |
dc.subject.MESH | Antibody Specificity/immunology | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child Welfare | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Dermatitis, Atopic/blood* | - |
dc.subject.MESH | Dermatitis, Atopic/immunology* | - |
dc.subject.MESH | Enterotoxins/immunology* | - |
dc.subject.MESH | Enterotoxins/pharmacology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoglobulin E/blood | - |
dc.subject.MESH | Immunoglobulin E/immunology | - |
dc.subject.MESH | Immunoglobulin G/blood | - |
dc.subject.MESH | Immunoglobulin G/immunology | - |
dc.subject.MESH | Immunoglobulin M/blood | - |
dc.subject.MESH | Immunoglobulin M/immunology | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infant Welfare | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Effect of staphylococcal enterotoxin B on specific antibody production in children with atopic dermatitis. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Sohn, Myung Hyun | - |
dc.contributor.googleauthor | Kim, Cheol Hong | - |
dc.contributor.googleauthor | Kim, Kyu-Earn | - |
dc.contributor.googleauthor | Jang, Gwang Cheon | - |
dc.contributor.googleauthor | Kim, Woo Kyung | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00327 | - |
dc.contributor.localId | A01967 | - |
dc.relation.journalcode | J00063 | - |
dc.identifier.eissn | 1539-6304 | - |
dc.identifier.pmid | 12635580 | - |
dc.identifier.url | http://www.ingentaconnect.com/content/ocean/aap/2003/00000024/00000001/art00010?token=0055173cea1a5bd275c277b42572b6756766b256245744a6d592f653b643d437c4e724770e9b991cd7a7a | - |
dc.subject.keyword | 12635580 | - |
dc.contributor.alternativeName | Kim, Kyu Earn | - |
dc.contributor.alternativeName | Son, Myung Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Kyu Earn | - |
dc.contributor.affiliatedAuthor | Son, Myung Hyun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 24 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 67 | - |
dc.citation.endPage | 71 | - |
dc.identifier.bibliographicCitation | ALLERGY AND ASTHMA PROCEEDINGS, Vol.24(1) : 67-71, 2003 | - |
dc.identifier.rimsid | 41865 | - |
dc.type.rims | ART | - |
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