Cited 6 times in
Preoperative Chemoradiation and Pancreaticoduodenectomy with Portal Vein Resection for Localized Advanced Pancreatic Cancer
DC Field | Value | Language |
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dc.contributor.author | 김경식 | - |
dc.date.accessioned | 2015-07-15T17:06:00Z | - |
dc.date.available | 2015-07-15T17:06:00Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/114225 | - |
dc.description.abstract | Pancreatic adenocarcinoma is a common disease that is rarely cured. Surgical resection remains the only treatment modality that has a curative potential, although the majority of patients are unsuitable for resection at the time of diagnosis. Chemoradiation therapy prior to a pancreaticoduodenectomy ensures that a patient who undergoes a complete resection multimodality therapy, avoids a resection in patients who have a rapidly progressive disease, and allows radiation therapy to be given to well oxygenated cells before, surgical devasculation. This permits the chance of resection of an unresectable pancreatic cancer by downstaging. A patient with cytologic proof of localized adenocarcinoma of the pancreatic head received an intravenously chemoradiation (Taxol, 50 mg/m2 intravenously for 3 hours week on 5 cycles, of Gemcytabine 1000 mg/m2/day intravenously for 3 days week on 2 cycles, of 4500 cGy) with the intention of proceeding to a resection operation, restaging was performed by computed tomography, magnetic resonance imaging from 5 weeks every months due to ongoing decreasing of tumor size after the chemoradiation. At laparotomy, the patient didn't have suspected metastatic disease, the tumor size was 2 × 3 cm on the pancreas head and was infiltrating into the portal vein for about 3 cm length on right side. A pancreaticoduodenectomy along with a portal vein and superior mesenteric vein resection was done and then reconstruction of a vascular anastomosis by using the right side of the internal jugular vein. Perioperative complications didn't occur. In conclusion, preoperative chemoradiation of a localized advanced pancreatic tumor has no added risk to the operative complications and the prospects for resectability are enhanced. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 551~556 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/diagnosis | - |
dc.subject.MESH | Adenocarcinoma/drug therapy | - |
dc.subject.MESH | Adenocarcinoma/radiotherapy | - |
dc.subject.MESH | Adenocarcinoma/surgery* | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pancreatic Neoplasms/diagnosis | - |
dc.subject.MESH | Pancreatic Neoplasms/drug therapy | - |
dc.subject.MESH | Pancreatic Neoplasms/radiotherapy | - |
dc.subject.MESH | Pancreatic Neoplasms/surgery* | - |
dc.subject.MESH | Pancreaticoduodenectomy* | - |
dc.subject.MESH | Preoperative Care* | - |
dc.title | Preoperative Chemoradiation and Pancreaticoduodenectomy with Portal Vein Resection for Localized Advanced Pancreatic Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Yoon Seok Chae | - |
dc.contributor.googleauthor | Jin Sub Choi | - |
dc.contributor.googleauthor | Byong Ro Kim | - |
dc.contributor.googleauthor | Woo Jung Lee | - |
dc.contributor.googleauthor | Jin Sil Seong | - |
dc.contributor.googleauthor | Kyung Sik Kim | - |
dc.identifier.doi | 10.3349/ymj.2003.44.3.551 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00299 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 12833599 | - |
dc.subject.keyword | Chemoradiation therapy | - |
dc.subject.keyword | pancreatic cancer | - |
dc.contributor.alternativeName | Kim, Kyung Sik | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Sik | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 44 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 551 | - |
dc.citation.endPage | 556 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.44(3) : 551-556, 2003 | - |
dc.identifier.rimsid | 41497 | - |
dc.type.rims | ART | - |
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