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Immediate reocclusion following a successful thrombolysis in acute stroke: A pilot study

Authors
 Ji Hoe Heo  ;  Kyung Yul Lee  ;  Dong Ik Kim  ;  Seo Hyun Kim 
Citation
 NEUROLOGY, Vol.60(10) : 1684-1687, 2003 
Journal Title
 NEUROLOGY 
ISSN
 0028-3878 
Issue Date
2003
MeSH
Abciximab ; Acute Disease ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/therapeutic use* ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/drug therapy ; Brain Ischemia/epidemiology* ; Cerebral Angiography ; Cerebral Arteries/diagnostic imaging ; Cerebral Arteries/drug effects* ; Cerebral Arteries/pathology ; Constriction, Pathologic ; Female ; Fibrinolytic Agents/therapeutic use* ; Humans ; Immunoglobulin Fab Fragments/administration & dosage ; Immunoglobulin Fab Fragments/therapeutic use* ; Male ; Middle Aged ; Pilot Projects ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/therapeutic use* ; Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors* ; Prospective Studies ; Recurrence ; Reperfusion ; Thrombolytic Therapy* ; Tissue Plasminogen Activator/therapeutic use ; Treatment Failure ; Urokinase-Type Plasminogen Activator/therapeutic use ; Vascular Patency*
Keywords
12771267
Abstract
Immediate reocclusion after successful thrombolysis was angiographically examined in 29 consecutive stroke patients. The reocclusion, which was associated with a high-grade residual stenosis of initially perfused arteries, occurred in four patients. IV abciximab successfully dissolved the thrombus in all four patients. Rapid thrombotic reocclusion after successful thrombolysis is commonly observed in patients after an acute stroke. Administration of abciximab may lead to reperfusion of the reoccluded artery.
Full Text
http://www.neurology.org/content/60/10/1684.long
DOI
10.1212/01.WNL.0000063323.23493.98
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Kyung Yul(이경열) ORCID logo https://orcid.org/0000-0001-5585-7739
Heo, Ji Hoe(허지회) ORCID logo https://orcid.org/0000-0001-9898-3321
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114135
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