0 416

Cited 31 times in

Primary NK/T Cell Lymphoma of the Testis: A case report and review of the literature

DC Field Value Language
dc.contributor.author김귀언-
dc.contributor.author서창옥-
dc.contributor.author양우익-
dc.contributor.author김용배-
dc.contributor.author심수정-
dc.date.accessioned2015-07-15T16:58:41Z-
dc.date.available2015-07-15T16:58:41Z-
dc.date.issued2003-
dc.identifier.issn0001-5792-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/113979-
dc.description.abstractWe report a case of aggressive ‘nasal type’ natural killer (NK)/T cell lymphoma initially presenting as a testicular tumor in a Korean man, which quickly took a fatal course by widespread dissemination. Histologically, the testicular mass showed a diffuse dense infiltrate of medium-sized and atypical large lymphoid cells with angiocentric and angiodestructive infiltration and areas of coagulative necrosis on hematoxylin-eosin stained sections. Immunophenotyping by immunohistochemistry yielded surface markers consistent with NK/T cell lymphoma. The Epstein-Barr virus genome was detected by in situ hybridization. During involved-field irradiation and chemotherapy following radical orchiectomy, the tumor disseminated shortly to the skin and soft tissue of his anterior chest wall and central nervous system (CNS). Identical lymphoid infiltrates were present in the patient’s skin. CNS involvement was interpreted as having a leptomeningeal seeding. To the best of our knowledge, this is the 9th reported case of confirmed NK/T cell lymphoma arising from the testis. Relevant literature is reviewed, and the clinicopathologic features, natural history, and treatment options for primary testicular NK/T cell lymphoma are discussed.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfACTA HAEMATOLOGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAntineoplastic Combined Chemotherapy Protocols/therapeutic use-
dc.subject.MESHCentral Nervous System/pathology-
dc.subject.MESHCyclophosphamide/therapeutic use-
dc.subject.MESHDoxorubicin/therapeutic use-
dc.subject.MESHFatal Outcome-
dc.subject.MESHHerpesvirus 4, Human/genetics-
dc.subject.MESHHumans-
dc.subject.MESHImmunohistochemistry-
dc.subject.MESHImmunophenotyping-
dc.subject.MESHIn Situ Hybridization-
dc.subject.MESHKiller Cells, Natural*-
dc.subject.MESHLymphoma, T-Cell/diagnosis*-
dc.subject.MESHLymphoma, T-Cell/pathology-
dc.subject.MESHLymphoma, T-Cell/therapy-
dc.subject.MESHMale-
dc.subject.MESHMethotrexate/therapeutic use-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNecrosis-
dc.subject.MESHNeoplasm Metastasis-
dc.subject.MESHOrchiectomy-
dc.subject.MESHPrednisone/therapeutic use-
dc.subject.MESHRNA, Viral/analysis-
dc.subject.MESHRadiotherapy-
dc.subject.MESHRecurrence-
dc.subject.MESHSkin/pathology-
dc.subject.MESHTesticular Neoplasms/diagnosis*-
dc.subject.MESHTesticular Neoplasms/pathology-
dc.subject.MESHTesticular Neoplasms/therapy-
dc.subject.MESHThoracic Wall/pathology-
dc.subject.MESHTomography, X-Ray Computed-
dc.subject.MESHUltrasonography-
dc.subject.MESHVincristine/therapeutic use-
dc.titlePrimary NK/T Cell Lymphoma of the Testis: A case report and review of the literature-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiation Oncology (방사선종양학)-
dc.contributor.googleauthorKim Y.B.-
dc.contributor.googleauthorChang S.K.-
dc.contributor.googleauthorKim G.E.-
dc.contributor.googleauthorSuh C.O.-
dc.contributor.googleauthorLee K.K.-
dc.contributor.googleauthorPark W.-
dc.contributor.googleauthorShim S.J.-
dc.contributor.googleauthorKoom W.S.-
dc.contributor.googleauthorHahn J.S.-
dc.contributor.googleauthorYang W.-I.-
dc.identifier.doi10.1159/000068489-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00321-
dc.contributor.localIdA01919-
dc.contributor.localIdA02300-
dc.relation.journalcodeJ00014-
dc.identifier.eissn1421-9662-
dc.identifier.pmid12624494-
dc.identifier.urlhttp://www.karger.com/Article/FullText/68489-
dc.subject.keywordTestocular lymphoma-
dc.subject.keywordNK/T cell lymphoma-
dc.contributor.alternativeNameKim, Gwi Eon-
dc.contributor.alternativeNameSuh, Chang Ok-
dc.contributor.alternativeNameYang, Woo Ick-
dc.contributor.affiliatedAuthorKim, Gwi Eon-
dc.contributor.affiliatedAuthorSuh, Chang Ok-
dc.contributor.affiliatedAuthorYang, Woo Ick-
dc.rights.accessRightsnot free-
dc.citation.volume109-
dc.citation.number2-
dc.citation.startPage95-
dc.citation.endPage100-
dc.identifier.bibliographicCitationACTA HAEMATOLOGICA, Vol.109(2) : 95-100, 2003-
dc.identifier.rimsid54033-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.