Cited 0 times in
Molecular genetics of cerebral aneurysm
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안정용 | - |
dc.date.accessioned | 2015-07-15T16:58:32Z | - |
dc.date.available | 2015-07-15T16:58:32Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 2234-8565 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/113974 | - |
dc.description.abstract | Subarachnoid hemorrhage(SAH) secondary to ruptured cerebral aneurysm is a complex trait, with both genetic and environmental risk factors playing an important part. The 30-day mortality rate of patients with SAH is 40% to 44%, with survivors suffering from major disability. Despite the high incidence and catastrophic consequences of a ruptured cerebral aneurysm and the fact that there is considerable evidence that predisposition to cerebral aneurysm has a strong genetic component, very little is understood with regard to the pathology and pathogenesis of this disease. Recent advances in molecular genetics provide evidence that genetic variants of different candidate genes are associated with the occurrence of cerebral aneurysm. This article reviews the evidence supporting a genetic predisposition to SAH from cerebral aneurysm, the conditions commonly associated with cerebral aneurysm, and the search for genetic risk factors. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | Korean Journal of Cerebrovascular Surgery (대한뇌혈관외과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Cerebral aneurysm | - |
dc.subject.MESH | Pathogenesis | - |
dc.subject.MESH | Molecular genetics | - |
dc.subject.MESH | Risk factors | - |
dc.subject.MESH | Genes | - |
dc.title | Molecular genetics of cerebral aneurysm | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학) | - |
dc.contributor.googleauthor | Jung Yong Ahn | - |
dc.contributor.googleauthor | Jin Kyeoung Kim | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02260 | - |
dc.relation.journalcode | J01975 | - |
dc.subject.keyword | Cerebral aneurysm | - |
dc.subject.keyword | Pathogenesis | - |
dc.subject.keyword | Molecular genetics | - |
dc.subject.keyword | Risk factors | - |
dc.subject.keyword | Genes | - |
dc.contributor.alternativeName | Ahn, Jung Yong | - |
dc.contributor.affiliatedAuthor | Ahn, Jung Yong | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 5 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 12 | - |
dc.citation.endPage | 16 | - |
dc.identifier.bibliographicCitation | Korean Journal of Cerebrovascular Surgery (대한뇌혈관외과학회지), Vol.5(1) : 12-16, 2003 | - |
dc.identifier.rimsid | 54029 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.