Cited 51 times in
Morphometric abnormality of the insula in schizophrenia: a comparison with obsessive–compulsive disorder and normal control using MRI
DC Field | Value | Language |
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dc.contributor.author | 김재진 | - |
dc.date.accessioned | 2015-07-15T16:50:35Z | - |
dc.date.available | 2015-07-15T16:50:35Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0920-9964 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/113707 | - |
dc.description.abstract | The insula is increasingly the subject of great interest in psychiatric disorders of neurodevelopmental origin because of its anatomical location, wide interconnectivity, and variety of functions. This study explores the possible morphometric change of the insula in schizophrenia and obsessive–compulsive disorder (OCD), and its potential relationship to clinical symptoms. The insula was traced on all coronal slices of magnetic resonance images of three age- and sex-matched diagnostic groups, which consisted of 21 patients with schizophrenia, 21 patients with OCD and 21 normal volunteers. The volumetric measures of the insula were compared among the three groups, and their relationships to the symptom severity were investigated. Volumetric reduction of the left insula was observed in the schizophrenia group, but not in the OCD group. These results confirm the involvement of deficient insular function in the pathophysiology of schizophrenia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 191~198 | - |
dc.relation.isPartOf | SCHIZOPHRENIA RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Cerebral Cortex/abnormalities* | - |
dc.subject.MESH | Cerebral Cortex/pathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/pathology* | - |
dc.subject.MESH | Schizophrenia/pathology* | - |
dc.title | Morphometric abnormality of the insula in schizophrenia: a comparison with obsessive–compulsive disorder and normal control using MRI | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | Jae-Jin Kim | - |
dc.contributor.googleauthor | Tak Youn | - |
dc.contributor.googleauthor | Jun Soo Kwon | - |
dc.contributor.googleauthor | Sun I Kim | - |
dc.contributor.googleauthor | In Young Kim | - |
dc.contributor.googleauthor | Jong Min Lee | - |
dc.identifier.doi | 10.1016/S0920-9964(02)00306-7 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00870 | - |
dc.relation.journalcode | J02641 | - |
dc.identifier.eissn | 1573-2509 | - |
dc.identifier.pmid | 12591583 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0920996402003067 | - |
dc.subject.keyword | Insula | - |
dc.subject.keyword | Paralimbic area | - |
dc.subject.keyword | Neurodevelopment | - |
dc.subject.keyword | MR volumetry | - |
dc.contributor.alternativeName | Kim, Jae Jin | - |
dc.contributor.affiliatedAuthor | Kim, Jae Jin | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 60 | - |
dc.citation.number | 2-3 | - |
dc.citation.startPage | 191 | - |
dc.citation.endPage | 198 | - |
dc.identifier.bibliographicCitation | SCHIZOPHRENIA RESEARCH, Vol.60(2-3) : 191-198, 2003 | - |
dc.identifier.rimsid | 49033 | - |
dc.type.rims | ART | - |
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