Cited 37 times in
Optimization of the Erbium : YAG Laser for Precise Ineision of Ureteral and Urethral Tissues : In Vitro and In Vivo Results
DC Field | Value | Language |
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dc.contributor.author | 나군호 | - |
dc.date.accessioned | 2015-07-15T16:42:10Z | - |
dc.date.available | 2015-07-15T16:42:10Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0196-8092 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/113427 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVES: Tissue damage during endoscopic treatment of urethral and ureteral strictures may result in stricture recurrence. The Erbium:YAG laser ablates soft tissues with minimal peripheral damage and may be a promising alternative to cold knife and Holmium:YAG laser for precise incision of urological strictures. STUDY DESIGN/MATERIALS AND METHODS: Optimization of the Er:YAG laser was conducted using ex vivo porcine ureteral and canine urethral tissues. Preliminary in vivo studies were also performed in a laparoscopic porcine ureteral model with exposed ureter. Laser radiation with a wavelength of 2.94 microm, pulse lengths of 8, 70, and 220 microseconds, output energies of 2-35 mJ, fluences of 1-25 J/cm2, and pulse repetition rates of 5-30 Hz, was delivered through 250-microm and 425-microm core germanium oxide optical fibers in direct contact with tissue. RESULTS: Ex vivo perforation thresholds measured 2-4 J/cm2, with ablation rates of 50 microm/pulse at fluences of 6-11 J/cm2. In vivo perforation thresholds were approximately 1.8 J/cm2, with the ureter perforated in less than 20 pulses at fluences greater than 3.6 J/cm2. Peripheral thermal damage in tissue decreased from 30 to 60 microm to 10-20 microm as the laser pulse length decreased from 220 to 8 microseconds. Mechanical tissue damage was observed at the 8 microseconds pulse duration. CONCLUSIONS: The Er:YAG laser, operating at a pulse duration of approximately 70 microseconds, a fluence greater than approximately 4 J/cm2, and a repetition rate less than 20 Hz, is capable of rapidly incising urethral and ureteral tissues with minimal thermal and mechanical side-effects. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 108~114 | - |
dc.relation.isPartOf | LASERS IN SURGERY AND MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | stricture | - |
dc.subject.MESH | urethra | - |
dc.subject.MESH | ureter | - |
dc.subject.MESH | Erbium | - |
dc.subject.MESH | Holmium | - |
dc.subject.MESH | laser | - |
dc.subject.MESH | ablation | - |
dc.subject.MESH | incision | - |
dc.title | Optimization of the Erbium : YAG Laser for Precise Ineision of Ureteral and Urethral Tissues : In Vitro and In Vivo Results | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨기과학) | - |
dc.contributor.googleauthor | Nathaniel M. Fried | - |
dc.contributor.googleauthor | Zelalem Tesfaye | - |
dc.contributor.googleauthor | Pooya Hejazi | - |
dc.contributor.googleauthor | Koon H. Rha | - |
dc.contributor.googleauthor | Albert M. Ong | - |
dc.identifier.doi | 10.1002/lsm.10205 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01227 | - |
dc.relation.journalcode | J02159 | - |
dc.identifier.eissn | 1096-9101 | - |
dc.identifier.pmid | 10.1002/lsm.10205 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/lsm.10205/abstract | - |
dc.subject.keyword | stricture | - |
dc.subject.keyword | urethra | - |
dc.subject.keyword | ureter | - |
dc.subject.keyword | Erbium | - |
dc.subject.keyword | Holmium | - |
dc.subject.keyword | laser | - |
dc.subject.keyword | ablation | - |
dc.subject.keyword | incision | - |
dc.contributor.alternativeName | Rha, Koon Ho | - |
dc.contributor.affiliatedAuthor | Rha, Koon Ho | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 33 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 108 | - |
dc.citation.endPage | 114 | - |
dc.identifier.bibliographicCitation | LASERS IN SURGERY AND MEDICINE, Vol.33(2) : 108-114, 2003 | - |
dc.identifier.rimsid | 49256 | - |
dc.type.rims | ART | - |
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