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관상동맥우회술 환자의 마취유도시 Fentanyl과 Vecuronium 사용으로 발생하는 서맥에 대한 Atropine의 약물 효과

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dc.contributor.author곽영란-
dc.contributor.author곽현정-
dc.date.accessioned2015-07-15T16:37:50Z-
dc.date.available2015-07-15T16:37:50Z-
dc.date.issued2003-
dc.identifier.issn0302-5780-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/113282-
dc.description.abstractBackground: Induction of anesthesia with a high dose of fentanyl and vecuronium decreases the heart rate and blood pressure. This study was designed to evaluate the effect of preinduction atropine on these hemodynamic changes in patients undergoing coronary artery bypass graft surgery (CABG). Methods: Forty-one patients who underwent CABG were randomly divided into two groups. After insertion of a radial artery cannula and a Swan-Ganz catheter, normal saline 1 ml (control group, n = 20) or atropine 0.5 mg (atropine group, n = 21) was injected intravenously 1 min before the induction of anesthesia. Anesthesia was induced with a first dose of fentanyl (5-8μg/ kg) and vecuronium (0.12 mg/kg) and a second dose of fentanyl (5-10μg/kg). The patient was then intubated. Hemodynamic variables were measured before the induction of anesthesia, 1 min after the administration of each drug during the induction of anesthesia and 5, 10, and 30 min after the intubation. Results: There was no significant differences between the two groups in terms of demographic data except that the number of patients with diabetes mellitus was greater in the control group than in the atropine group. The number of patients treated for hypotension or bradycardia during the induction of anesthesia was greater in the control group than in the atropine group, but this was not statistically significant. Heart rates significantly decreased in the control group but were maintained in the atropine group without any significant tachycardia. Blood pressure significantly decreased in both groups. Conclusions: Intravenous injection of atropine before anesthetic induction in patients undergoing CABG attenuates the decrease in heart rate resulting from anesthetic induction with high dose fentanyl and vecuronium. However, it didn't prevent the decrease in blood pressure nor did it reduce the incidence of treatment for hypotension.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfJournal of Korean Society of Anesthesiologist (대한마취과학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAtropine-
dc.subject.MESHbradycardia-
dc.subject.MESHcoronary artery bypass graft surgery-
dc.subject.MESHfentanyl-
dc.subject.MESHvecuronium-
dc.title관상동맥우회술 환자의 마취유도시 Fentanyl과 Vecuronium 사용으로 발생하는 서맥에 대한 Atropine의 약물 효과-
dc.title.alternativeEffects of Preinduction Atropine on the Hemody namic Response to Induction with Fentanyl and Vecuronium for Coronary Artery Bypass Grafting-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthor곽현정-
dc.contributor.googleauthor이우경-
dc.contributor.googleauthor곽영란-
dc.contributor.googleauthor박근모-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00172-
dc.contributor.localIdA00184-
dc.relation.journalcodeJ01540-
dc.subject.keywordAtropine-
dc.subject.keywordbradycardia-
dc.subject.keywordcoronary artery bypass graft surgery-
dc.subject.keywordfentanyl-
dc.subject.keywordvecuronium-
dc.contributor.alternativeNameKwak, Young Lan-
dc.contributor.alternativeNameKwak, Hyun Jeong-
dc.contributor.affiliatedAuthorKwak, Young Lan-
dc.contributor.affiliatedAuthorKwak, Hyun Jeong-
dc.rights.accessRightsfree-
dc.citation.volume44-
dc.citation.number5-
dc.citation.startPage626-
dc.citation.endPage632-
dc.identifier.bibliographicCitationJournal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.44(5) : 626-632, 2003-
dc.identifier.rimsid55800-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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