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CD34음성 비아세포성 성숙골수계 세포에서 비정상적인 N-CAM (CD56)항원 발현을 보인 만성골수성백혈병 1예
DC Field | Value | Language |
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dc.contributor.author | 이경아 | - |
dc.date.accessioned | 2015-07-14T17:26:23Z | - |
dc.date.available | 2015-07-14T17:26:23Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1598-6535 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/112884 | - |
dc.description.abstract | The CD56 antigen is a cell adhesion molecule and its expression on tumor cells is thought to play a role in CD56-positive lymphomas and leukemias with unusual sites of involvement. As to chronic myelogenous leukemia (CML) and related blastic crisis, CD56 expression is not generally considered as a part of the CML phenotype and has rarely been reported in CML and other chronic myelopro¬liferative dirsorders (CMPD). We reported a case of CML expressing the CD56 antigen on the CD34¬negative myeloid cells presented with extramedullary granulocytic sarcoma and examined the CD56 reactivity on bone marrow biopsy sections in 9 patients with CMPD. To assess the abnormal expres¬sion of the CD56 antigen on myeloid and progenitor cells from CMPD, immunohistochemical staining and flow cytometric analysis were performed on bone marrow biopsy sections and aspirate speci¬mens, respectively. Of nine patients with CMPD, a case of CML in blastic crisis with extramedullary granulocytic sarcoma showed an abnormal expression of CD56 on CD34-negative myeloid cells. The expression of CD56 on CML myeloid elements seems to represent an aberrant phenomenon that could affect the pattern of tumor cell dissemination. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1~6 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | CD34음성 비아세포성 성숙골수계 세포에서 비정상적인 N-CAM (CD56)항원 발현을 보인 만성골수성백혈병 1예 | - |
dc.title.alternative | A Case of Chronic Myelogenous Leukemia with Abnormal Expression of N-CAM (CD56)Adhesion Molecule on CD34-negative Non-blastic Myeloid Cells | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | 이경아 | - |
dc.contributor.googleauthor | 류숙원 | - |
dc.contributor.googleauthor | 김병수 | - |
dc.contributor.googleauthor | 김영기 | - |
dc.contributor.googleauthor | 조윤정 | - |
dc.contributor.googleauthor | 김경희 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02647 | - |
dc.relation.journalcode | J02045 | - |
dc.subject.keyword | CD56 | - |
dc.subject.keyword | Chronic myelogenous leukemia | - |
dc.subject.keyword | Myeloid cells | - |
dc.subject.keyword | Extramedullary granulocytic | - |
dc.subject.keyword | sarcoma | - |
dc.contributor.alternativeName | Lee, Kyung A | - |
dc.contributor.affiliatedAuthor | Lee, Kyung A | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 24 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 6 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF LABORATORY MEDICINE , Vol.24(1) : 1-6, 2004 | - |
dc.identifier.rimsid | 36772 | - |
dc.type.rims | ART | - |
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