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CD34음성 비아세포성 성숙골수계 세포에서 비정상적인 N-CAM (CD56)항원 발현을 보인 만성골수성백혈병 1예

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dc.contributor.author이경아-
dc.date.accessioned2015-07-14T17:26:23Z-
dc.date.available2015-07-14T17:26:23Z-
dc.date.issued2004-
dc.identifier.issn1598-6535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/112884-
dc.description.abstractThe CD56 antigen is a cell adhesion molecule and its expression on tumor cells is thought to play a role in CD56-positive lymphomas and leukemias with unusual sites of involvement. As to chronic myelogenous leukemia (CML) and related blastic crisis, CD56 expression is not generally considered as a part of the CML phenotype and has rarely been reported in CML and other chronic myelopro¬liferative dirsorders (CMPD). We reported a case of CML expressing the CD56 antigen on the CD34¬negative myeloid cells presented with extramedullary granulocytic sarcoma and examined the CD56 reactivity on bone marrow biopsy sections in 9 patients with CMPD. To assess the abnormal expres¬sion of the CD56 antigen on myeloid and progenitor cells from CMPD, immunohistochemical staining and flow cytometric analysis were performed on bone marrow biopsy sections and aspirate speci¬mens, respectively. Of nine patients with CMPD, a case of CML in blastic crisis with extramedullary granulocytic sarcoma showed an abnormal expression of CD56 on CD34-negative myeloid cells. The expression of CD56 on CML myeloid elements seems to represent an aberrant phenomenon that could affect the pattern of tumor cell dissemination.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1~6-
dc.relation.isPartOfKOREAN JOURNAL OF LABORATORY MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCD34음성 비아세포성 성숙골수계 세포에서 비정상적인 N-CAM (CD56)항원 발현을 보인 만성골수성백혈병 1예-
dc.title.alternativeA Case of Chronic Myelogenous Leukemia with Abnormal Expression of N-CAM (CD56)Adhesion Molecule on CD34-negative Non-blastic Myeloid Cells-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthor이경아-
dc.contributor.googleauthor류숙원-
dc.contributor.googleauthor김병수-
dc.contributor.googleauthor김영기-
dc.contributor.googleauthor조윤정-
dc.contributor.googleauthor김경희-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02647-
dc.relation.journalcodeJ02045-
dc.subject.keywordCD56-
dc.subject.keywordChronic myelogenous leukemia-
dc.subject.keywordMyeloid cells-
dc.subject.keywordExtramedullary granulocytic-
dc.subject.keywordsarcoma-
dc.contributor.alternativeNameLee, Kyung A-
dc.contributor.affiliatedAuthorLee, Kyung A-
dc.rights.accessRightsfree-
dc.citation.volume24-
dc.citation.number1-
dc.citation.startPage1-
dc.citation.endPage6-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF LABORATORY MEDICINE , Vol.24(1) : 1-6, 2004-
dc.identifier.rimsid36772-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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