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전립선 비대증 환자에서 알파 1 교감신경수용체 차단제 Tamsulosin이 성기능에 미치는 영향
DC Field | Value | Language |
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dc.contributor.author | 정병하 | - |
dc.contributor.author | 홍성준 | - |
dc.date.accessioned | 2015-07-14T17:25:29Z | - |
dc.date.available | 2015-07-14T17:25:29Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1229-1692 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/112854 | - |
dc.description.abstract | Purpose: We evaluated the effectiveness of alpha 1 adrenoceptor antagonist tamsulosin on erectile function in the treatment of the patients with benign prostatic hyperplasia(BPH). Materials and Methods: We recruited 268 patients who had BPH with lower urinary tract symptoms in the period of June 2003 to September 2003. The study utilized an open-label approach. Patients were evaluated by physical examination, transrectal ultrasonography(TRUS), serum prostate specific antigen(PSA), uroflowmetry, international prostatic symptom score(IPSS), quality of life(QOL) assessment, voiding diary for 3 days, brief international index of erectile function(IIEF)-7 score, and the global efficacy assessment questionnaire(GEAQ)-2. All evaluations were performed before medication, and again at 4 and 12 weeks of treatment. The patients suspected to have prostatic carcinoma based on the digital rectal examination and/or PSA level above 4 ng/ml underwent transrectal ultrasonography guided biopsy of the prostate. The patients found to have prostate cancer were not included in the study. Results: A total of 165 patients completed the study. Total IIEF scores did not change significantly. Question 10 of IIEF was significantly different between 4 and 12 weeks. There was a statistically significant difference in GEAQ-2 between 4 and 12 weeks of medication. Ejaculation volume decreased 14% and 22% at 4 and 12 weeks, respectively. However, orgasmic function significantly improved between 4 and 12 weeks. Conclusions: In patients with BPH, tamsulosin therapy improved sexual and orgasmic function, although it decreased ejaculation volume. We need a longer follow-up period and more patients to establish the effects of tamsulosin on erectile function in the patients with BPH. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 146~150 | - |
dc.relation.isPartOf | Korean Journal of Andrology (대한남성과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 전립선 비대증 환자에서 알파 1 교감신경수용체 차단제 Tamsulosin이 성기능에 미치는 영향 | - |
dc.title.alternative | Effects of Alpha 1 Adrenoceptor Antagonist Tamsulosin on Sexual Function in Patients with Benign Prostatic Hyperplasia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨기과학) | - |
dc.contributor.googleauthor | 박종관 | - |
dc.contributor.googleauthor | 김청수 | - |
dc.contributor.googleauthor | 홍성준 | - |
dc.contributor.googleauthor | 정병하 | - |
dc.contributor.googleauthor | 이정구 | - |
dc.contributor.googleauthor | 박철희 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03607 | - |
dc.contributor.localId | A04402 | - |
dc.relation.journalcode | J01962 | - |
dc.subject.keyword | Benign prostatic hyperplasia | - |
dc.subject.keyword | Alpha 1 adrenoceptor antagonist tamsulosin | - |
dc.contributor.alternativeName | Chung, Byung Ha | - |
dc.contributor.alternativeName | Hong, Sung Joon | - |
dc.contributor.affiliatedAuthor | Chung, Byung Ha | - |
dc.contributor.affiliatedAuthor | Hong, Sung Joon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 22 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 146 | - |
dc.citation.endPage | 150 | - |
dc.identifier.bibliographicCitation | Korean Journal of Andrology (대한남성과학회지), Vol.22(3) : 146-150, 2004 | - |
dc.identifier.rimsid | 36755 | - |
dc.type.rims | ART | - |
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