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A case of lactic acidosis caused by stavudine in an AIDS patient
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김준명 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 조병철 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2015-07-14T17:23:10Z | - |
dc.date.available | 2015-07-14T17:23:10Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/112776 | - |
dc.description.abstract | Nucleoside reverse transcriptase inhibitors (NRTIs), which are used for the treatment of human immunodeficiency virus (HIV) infection have been associated with a wide spectrum of clinical manifestations, including hepatic steatosis, lipodystrophy, myopathy, and lactic acidosis. Such adverse effects are postulated to result from the inhibition of mitochondrial DNA gamma polymerase, which causes the depletion of mitochondrial DNA and eventual the disruption of oxidative phosphorylation. Although cases of severe decompensated lactic acidosis are rare, this syndrome is associated with a high mortality rate. We report upon the first Korean case, of severe lactic acidosis in an acquired immunodeficiency syndrome (AIDS) patient receiving stavudine, an anti-HIV drug. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 66~69 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acidosis, Lactic/chemically induced* | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome/drug therapy* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anti-HIV Agents/adverse effects* | - |
dc.subject.MESH | Anti-HIV Agents/therapeutic use | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Sodium Bicarbonate/therapeutic use | - |
dc.subject.MESH | Stavudine/adverse effects* | - |
dc.subject.MESH | Stavudine/therapeutic use | - |
dc.title | A case of lactic acidosis caused by stavudine in an AIDS patient | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Byoung Chul Cho | - |
dc.contributor.googleauthor | Sang Hoon Han | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.contributor.googleauthor | Young Goo Song | - |
dc.contributor.googleauthor | Kyung Hee Chang | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Suk Hoon Choi | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A03822 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J02883 | - |
dc.identifier.eissn | 2005-6648 | - |
dc.identifier.pmid | 15053048 | - |
dc.subject.keyword | Lactic acidosis | - |
dc.subject.keyword | Stavudine | - |
dc.subject.keyword | HIV | - |
dc.subject.keyword | Anti-HIV Drugs | - |
dc.subject.keyword | Acquired Immunodeficiency Syndrome | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Song, Young Goo | - |
dc.contributor.alternativeName | Cho, Byoung Chul | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Song, Young Goo | - |
dc.contributor.affiliatedAuthor | Cho, Byoung Chul | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 19 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 66 | - |
dc.citation.endPage | 69 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, Vol.19(1) : 66-69, 2004 | - |
dc.identifier.rimsid | 44498 | - |
dc.type.rims | ART | - |
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