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The correlation between insulin resistance and the visceral fat to skeletal muscle ratio in middle-aged women

DC FieldValueLanguage
dc.contributor.author이현철-
dc.contributor.author임승길-
dc.contributor.author차봉수-
dc.contributor.author허갑범-
dc.contributor.author김경래-
dc.contributor.author김똘미-
dc.contributor.author김철식-
dc.contributor.author남주영-
dc.contributor.author박종석-
dc.contributor.author안철우-
dc.date.accessioned2015-07-14T17:16:39Z-
dc.date.available2015-07-14T17:16:39Z-
dc.date.issued2004-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/112561-
dc.description.abstractCentral obesity with visceral fat accumulation and the amount of skeletal muscle mass may influence insulin sensitivity via its capacity for glucose load uptake. We investigated the relationships among the following metabolic variables: ratio of fat area to skeletal muscle area (VMR), percent ideal body weight, body mass index, waist-to-hip circumference (WHR) and visceral fat to subcutaneous fat ratio (VSR) in 114 nondiabetic middle-aged women. Anthropometric parameters, lipid profiles and sex hormone-binding globulin were measured. Visceral and subcutaneous fat areas at the umbilical level and the skeletal muscle area at the mid-thigh level were measured and computed. 75-gram OGTT tests were performed, along with measuring plasma glucose, insulin and free fatty acid levels, according to which area under the curve of glucose (Glu-AUC), insulin (Ins-AUC), free fatty acid (FFA-AUC) and glucose/insulin ratio (GIR=Glu- AUC/Ins-AUC), were calculated. 1) Triglyceride was more correlated with VSR than VMR. 2) The independent anthropometric parameters for each metabolic variable were In conclusion, VMR for Ins-AUC, WHR for Glu-AUC and total cholesterol, and VSR for triglyceride. 3) For subjects with higher VMR, age, Ins-AUC and triglyceride were significantly higher. 4) Subjects with higher VMR were older and showed higher Ins-AUC and lower GIR than the subjects with lower VMR. In conclusion, VMR is an anthropometric parameter that reflects insulin resistance concerning glucose metabolism, and VSR is thought to be a good parameter that that reflects the serum lipid levels. Further prospective studies are necessary to reevaluate the visceral fat vs. skeletal muscle relationship.-
dc.description.statementOfResponsibilityopen-
dc.format.extent469~478-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdipose Tissue/metabolism*-
dc.subject.MESHAdipose Tissue/pathology*-
dc.subject.MESHAdult-
dc.subject.MESHBody Constitution-
dc.subject.MESHBody Mass Index*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInsulin Resistance*-
dc.subject.MESHMenopause-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMuscle, Skeletal/metabolism*-
dc.subject.MESHObesity/metabolism-
dc.subject.MESHObesity/pathology-
dc.subject.MESHPostmenopause-
dc.subject.MESHViscera-
dc.titleThe correlation between insulin resistance and the visceral fat to skeletal muscle ratio in middle-aged women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorChul Sik Kim-
dc.contributor.googleauthorJoo Young Nam-
dc.contributor.googleauthorBong Soo Cha-
dc.contributor.googleauthorKap Bum Huh-
dc.contributor.googleauthorHyun Chul Lee-
dc.contributor.googleauthorKyung Rae Kim-
dc.contributor.googleauthorSung Kil Lim-
dc.contributor.googleauthorChul Woo Ahn-
dc.contributor.googleauthorSoo Jee Yoon-
dc.contributor.googleauthorDol Mi Kim-
dc.contributor.googleauthorJong Suk Park-
dc.identifier.doi10.3349/ymj.2004.45.3.469-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid15227734-
dc.subject.keywordInsulin resistance-
dc.subject.keywordvisceral fat-
dc.subject.keywordskeletal muscle-
dc.subject.keywordvisceral fat to skeletal muscle ratio-
dc.subject.keywordvisceral fat to subcutaneous fat ratio-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameLim, Sung Kil-
dc.contributor.alternativeNameCha, Bong Soo-
dc.contributor.alternativeNameHuh, Kap Bum-
dc.contributor.alternativeNameKim, Kyung Rae-
dc.contributor.alternativeNameKim, Dol Mi-
dc.contributor.alternativeNameKim, Chul Sik-
dc.contributor.alternativeNameNam, Ju Young-
dc.contributor.alternativeNamePark, Jong Suk-
dc.contributor.alternativeNameAhn, Chul Woo-
dc.rights.accessRightsfree-
dc.citation.volume45-
dc.citation.number3-
dc.citation.startPage469-
dc.citation.endPage478-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.45(3) : 469-478, 2004-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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