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Role of flagellum and motility in pathogenesis of Vibrio vulnificus
- Authors
- Jong-Ho Lee ; Jong Bok Rho ; Soon-Jung Park ; Kyu-Ho Lee ; Sang Ho Choi ; Yang-Soo Han ; Chang Beom Kim ; Kyung-Je Park
- Citation
- INFECTION AND IMMUNITY, Vol.72(8) : 4905-4910, 2004
- Journal Title
- INFECTION AND IMMUNITY
- ISSN
- 0019-9567
- Issue Date
- 2004
- MeSH
- Animals ; Bacterial Adhesion ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biofilms/growth & development ; Cell Line ; Female ; Flagella/physiology* ; Humans ; Mice ; Mice, Inbred ICR ; Molecular Sequence Data ; Movement* ; Mutation ; Vibrio Infections/microbiology ; Vibrio Infections/mortality ; Vibrio vulnificus/genetics ; Vibrio vulnificus/pathogenicity* ; Vibrio vulnificus/physiology
- Abstract
- To assess the role of the flagellum which was detected by immunoscreening of surface proteins of Vibrio vulnificus, an flgE-deleted mutant was constructed and tested for its pathogenicity. The ability of this nonmotile mutant to adhere to INT-407 cells and its role in biofilm were decreased, as was its lethality to mice.
- Files in This Item:
- T200401302.pdf Download
- Appears in Collections:
- 1. College of Medicine (의과대학) > Dept. of Tropica Medicine (열대의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
- Yonsei Authors
-
Park, Soon Jung(박순정)
https://orcid.org/0000-0002-0423-1944
Lee, Kyu Ho(이규호)
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