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위암 환자의 생존율 분석에 근거한 새로운 병기분류법의 제안
DC Field | Value | Language |
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dc.contributor.author | 김준억 | - |
dc.contributor.author | 노성훈 | - |
dc.contributor.author | 정재호 | - |
dc.contributor.author | 최승호 | - |
dc.contributor.author | 형우진 | - |
dc.date.accessioned | 2015-07-14T17:04:27Z | - |
dc.date.available | 2015-07-14T17:04:27Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1226-0053 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/112152 | - |
dc.description.abstract | Purpose: This study was carried out to propose a new staging system to improve the current UICC/AJCC staging system. Methods: A total of 4217 patients who had undergone gastrectomy for gastric cancer from 1987 to 1997 were retrospectively reviewed. Among them, 4040 patients with either early gastric cancer (EGC, n=1202) or advanced gastric cancer (AGC, n=2838) can be appropriately staged by the 6th UICC/AJCC system. Survival rates of EGC were analyzed according to the number of lymph node metastasis while those of AGC patients were analyzed according to the TNM classifications. Results: The 5-year survival rate (5-YSR) of EGC patients according to the 6th UICC/AJCC was 94.6% for stage Ⅰa, 92.9% for stage Ⅰb, and 40.9% for stage Ⅱ or Ⅳ. The 5-YSR according to the number of lymph node metastases in EGC patients was 94.6% for EGC patients with node negative, 95.1% for those with 1 or 2 positive nodes, and 73.4% for those with 3 or more positive nodes. The 95% confidence intervals of mean survival duration were narrower when patients were grouped with a reference number of metastatic lymph nodes as 3 than when patients were grouped according to the 6th UICC/AJCC staging system. The 5-YSR according to TNM classifications in AGC patients wss 89.8% for T2N0M0, 71.5% for T2N1M0, 74.9% for T3N0M0, 55.2% for T2N2M0, 58.6% for T3N1M0, 44.4% for T4N0M0, 35.1% for T3N2M0, 32.3% for T4N1M0, 9.4% for T4N2M0, 14.1% for TanyN3M0, and 7.6% for TanyNanyM1 The survival of T4N1M0 was rather similar to that of T3N2M0 (P=0.9225) than other TNM classifications in stage Ⅳ (P<0.0001). Conclusion: With these results we may propose following new staging proposal. For EGC patients, the following division of N1 into two groups is recommanded: 1 or 2 positive lymph nodes as N1a and 3 or more positive nodes as N1b is recommended. With the new nodal classification in EGC, the staging recommendation for EGC patients is Ⅰ for T1N0M0 and T1N1aM0, and Ⅱ for T1N1bM0. For AGC patients, the following redistribution of TNM classification is recommanded for a new staging system, regarding T2N0M0 as stage Ⅰ and T4N1M0 as stage Ⅲb. In this new staging system, we can reduce the 6 stage groups into 5. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 20~26 | - |
dc.publisher | 대한외과학회 | - |
dc.relation.isPartOf | JOURNAL OF THE KOREAN SURGICAL SOCIETY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 위암 환자의 생존율 분석에 근거한 새로운 병기분류법의 제안 | - |
dc.title.alternative | A Proposal of New Staging System Based on Survival Rates in Gastric Cancer Patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | 형우진 | - |
dc.contributor.googleauthor | 정재호 | - |
dc.contributor.googleauthor | 노성훈 | - |
dc.contributor.googleauthor | 최승호 | - |
dc.contributor.googleauthor | 첸지안 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.relation.journalcode | J01893 | - |
dc.subject.keyword | Gastric cancer | - |
dc.subject.keyword | Stage | - |
dc.subject.keyword | Staging system | - |
dc.subject.keyword | Survival rate | - |
dc.subject.keyword | 위암 | - |
dc.subject.keyword | 병기 | - |
dc.subject.keyword | 병기분류법 | - |
dc.subject.keyword | 생존율 | - |
dc.contributor.alternativeName | Kim, Jun Uk | - |
dc.contributor.alternativeName | Noh, Sung Hoon | - |
dc.contributor.alternativeName | Cheong, Jae Ho | - |
dc.contributor.alternativeName | Choi, Seung Ho | - |
dc.contributor.alternativeName | Hyung, Woo Jin | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 66 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 20 | - |
dc.citation.endPage | 26 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE KOREAN SURGICAL SOCIETY , Vol.66(1) : 20-26, 2004 | - |
dc.identifier.rimsid | 45404 | - |
dc.type.rims | ART | - |
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