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원발성 종격동 종양 및 낭종의 진단과 치료 : 단일 대학병원에서의 42년 보고

Other Titles
 Diagnosis and Treatment of Primary Mediastinal Tumors and Cysts -Forty-two years report in a University Hospital- 
 박무석  ;  정경영  ;  김형중  ;  김세규  ;  신동환  ;  김영삼  ;  문진욱  ;  한창훈  ;  정재호  ;  이홍렬  ;  김길동 
Journal Title
Issue Date
Mediastinal tumors ; Cysts ; Diagnosis ; Treatment.
Background : The diagnostic and therapeutic approaches to mediastinal tumors and cysts have changed over the past three decades. This report summarizes our forty-two years of experience with these tumors. Materials and Methods : This study retrospectively reviewed 479 patients with primary mediastinal tumors and cysts that were diagnosed and managed over the past 17-year period (1985~2002) and compared them to the report of the previous 25-year result (1960~1985) in Yonsei University College of Medicine, Severance Hospital in Seoul, Korea. Results : During the 17 years, there were 479 cases of pathologically proven mediastinal tumors and cysts. Thymoma (38.2%) was the most common mediastinal tumor and has increased noticeably during recent years. The gender ratio showed a male predominance (1.3:1) and the age distributions were even over all the age groups. The most common sites of the tumor and the proportion(28.6%) of malignant tumors were the same as that previously reported. A diagnosis of a tumor in asymptomatic patients was possible in 174 cases (36.3%), which was higher that reported previously.  The diagnostic yield of a fine needle aspiration biopsy was 68.6% in the total tumors and 80.9% in the malignant tumors. A surgical resection was the most frequently chosen treatment modality and was performed in 405 cases (84.6%). The complete resection rate was 91.1%, which is higher than the previous result of 78.8%. Conclusion : These results showed that the prevalence of mediastinal tumors and cysts, particularly thymoma, increased. A fine needle aspiration biopsy was a valuable preoperative differential diagnostic method for malignant tumors. The surgical and complete resection rate increased remarkably possibly due to the better applicable chest CT scans, the more frequent health check-up provided by the regular health promotion program for all people as a health insurance policy, and the improved diagnostic techniques in the pathologic, radiological, and clinical fields.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kil Dong(김길동)
Kim, Sung Kyu(김성규)
Kim, Se Kyu(김세규)
Kim, Young Sam(김영삼) ORCID logo https://orcid.org/0000-0001-9656-8482
Kim, Hyung Jung(김형중) ORCID logo https://orcid.org/0000-0003-2498-0683
Moon, Jin Wook(문진욱)
Park, Moo Suk(박무석) ORCID logo https://orcid.org/0000-0003-0820-7615
Shin, Dong Hwan(신동환)
Ahn, Chul Min(안철민)
Lee, Hong Lyeol(이홍렬)
Chang, Joon(장준) ORCID logo https://orcid.org/0000-0003-4542-6841
Chung, Kyung Young(정경영)
Chung, Jae Ho(정재호)
Hahn, Chang Hoon(한창훈)
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