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원발성 종격동 종양 및 낭종의 진단과 치료 : 단일 대학병원에서의 42년 보고

Other Titles
 Diagnosis and Treatment of Primary Mediastinal Tumors and Cysts -Forty-two years report in a University Hospital- 
Authors
 박무석  ;  정경영  ;  김형중  ;  김세규  ;  신동환  ;  김영삼  ;  문진욱  ;  한창훈  ;  정재호  ;  이홍렬  ;  김길동 
Citation
 Tuberculosis and Respiratory Diseases, Vol.56(1) : 29-39, 2004 
Journal Title
 Tuberculosis and Respiratory Diseases 
ISSN
 0378-0066 
Issue Date
2004
Abstract
Background : The diagnostic and therapeutic approaches to mediastinal tumors and cysts have changed over the past three decades. This report summarizes our forty-two years of experience with these tumors. Materials and Methods : This study retrospectively reviewed 479 patients with primary mediastinal tumors and cysts that were diagnosed and managed over the past 17-year period (1985~2002) and compared them to the report of the previous 25-year result (1960~1985) in Yonsei University College of Medicine, Severance Hospital in Seoul, Korea. Results : During the 17 years, there were 479 cases of pathologically proven mediastinal tumors and cysts. Thymoma (38.2%) was the most common mediastinal tumor and has increased noticeably during recent years. The gender ratio showed a male predominance (1.3:1) and the age distributions were even over all the age groups. The most common sites of the tumor and the proportion(28.6%) of malignant tumors were the same as that previously reported. A diagnosis of a tumor in asymptomatic patients was possible in 174 cases (36.3%), which was higher that reported previously.  The diagnostic yield of a fine needle aspiration biopsy was 68.6% in the total tumors and 80.9% in the malignant tumors. A surgical resection was the most frequently chosen treatment modality and was performed in 405 cases (84.6%). The complete resection rate was 91.1%, which is higher than the previous result of 78.8%. Conclusion : These results showed that the prevalence of mediastinal tumors and cysts, particularly thymoma, increased. A fine needle aspiration biopsy was a valuable preoperative differential diagnostic method for malignant tumors. The surgical and complete resection rate increased remarkably possibly due to the better applicable chest CT scans, the more frequent health check-up provided by the regular health promotion program for all people as a health insurance policy, and the improved diagnostic techniques in the pathologic, radiological, and clinical fields.
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Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실)
Yonsei Authors
김길동(Kim, Kil Dong)
김성규(Kim, Sung Kyu)
김세규(Kim, Se Kyu)
김영삼(Kim, Young Sam) ORCID logo https://orcid.org/0000-0001-9656-8482
김형중(Kim, Hyung Jung) ORCID logo https://orcid.org/0000-0003-2498-0683
문진욱(Moon, Jin Wook)
박무석(Park, Moo Suk) ORCID logo https://orcid.org/0000-0003-0820-7615
신동환(Shin, Dong Hwan)
안철민(Ahn, Chul Min)
이홍렬(Lee, Hong Lyeol)
장준(Chang, Joon) ORCID logo https://orcid.org/0000-0003-4542-6841
정경영(Chung, Kyung Young)
정재호(Chung, Jae Ho)
한창훈(Hahn, Chang Hoon)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/112147
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