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뒤시엔느형 근디스트로피 환자의 심장기능 평가

Other Titles
 The Evaluation of Cardiac Function in Duchenne Muscular Dystrophy 
 강성웅  ;  임상희  ;  허현석  ;  박사윤  ;  문재호 
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지), Vol.28(6) : 559-564, 2004 
Journal Title
Journal of the Korean Academy of Rehabilitation Medicine(대한재활의학회지)
Issue Date
Duchenne muscular dystrophy ; Cardiomyopathy ; Echocardiography ; Electrocardiography
Objective: To evaluate the cardiac function and to explore the importance of the evaluation of cardiac function in patients with Duchenne muscular dystrophy (DMD). Method: Thirty-nine patients with DMD without any symptoms of heart problems underwent physical examinations and cardiac monitoring including the arterial carbon dioxide (CO2) screening. Thirty one patients underwent pulmonary function test. Results: Among 39 patients 27 showed abnormal electrocardiographic findings such as ventricular hypertrophy, ischemic change, atrial hypertrophy, T wave inversion, sinus tachycardia and ST elevation. 24 patients showed abnormal echocardiographic findings such as abnormal ejection fraction, dilated cardiomyopathy (DCMP), filling abnormality of left ventricle, global hypokinesia and reduced systolic function. 17 patients showed low ejection fraction (below 59%) and 4 of them were diagnosed as DCMP. There were significant correlations between age and ejection fraction (r=⁣0.552, p<0.01), between functional level and ejection fraction (r=⁣0.607, p<0.01) and between vital capacity and ejection fraction (r=0.547, p<0.01). However, ejection fraction showed no significant correlations with arterial CO2. Conclusion: Routine evaluation of the cardiac function, at least from 10 years of age, and proper treatment following early diagnosis of heart problems were necessary in patients with DMD, because they possibly have been severely affected by cardiac problems without any clinical symptoms.
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1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seong Woong(강성웅) ORCID logo https://orcid.org/0000-0002-7279-3893
Moon, Jae Ho(문재호)
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