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당뇨병성 위마비증 환자에서 유문륜내 보툴리눔독소의 주사 치험 4예

Other Titles
 Pyloric Injection of Botulinum Toxin for Treatment of Diabetic Gastroparesis: A Report of Four Cases 
Authors
 김민수  ;  이용찬  ;  이현철  ;  안철우  ;  박종관  ;  정연수  ;  이정은  ;  박효진 
Citation
 Korean Journal of Gastrointestinal Endoscopy (대한소화기내시경학회지), Vol.29(2) : 70-74, 2004 
Journal Title
Korean Journal of Gastrointestinal Endoscopy(대한소화기내시경학회지)
ISSN
 1225-7001 
Issue Date
2004
Keywords
당뇨병성 위마비증 ; 유문륜 ; 보툴리눔독소 ; Diabetic gastroparesis ; Pylorus ; Botulinum toxin
Abstract
Gastroparesis is a disorder of gastric motility that results in delayed gastric emptying. Up to 58% of patients with diabetes mellitus may have diabetic gastroparesis, a syndrome characterized by nausea, vomiting, early satiety, and bloating. The pathophysiology of this disorder is not completely understood, but it is believed to include fundic dysaccommodation, a decrease in gastroduodenal pressure gradient and antral hypomotility. In addition to antral and fundic dysfunction, patients with diabetes may typically have pyloric dysfunction or spasm. Treatment consists of a change in diet to small volume, frequent meals and the use of the prokinetic agents. This case report describes the four patients with severe diabetic gastroparesis whose symptoms persisted despite of dietary changes and the use of prokinetic agents in high doses. All of them were treated with pyloric injection of botulinum toxin and three had significant symptomatic and scintigraphic improvement.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Yong Chan(이용찬) ORCID logo https://orcid.org/0000-0001-8800-6906
Lee, Jung Eun(이정은) ORCID logo https://orcid.org/0000-0003-0917-2872
Lee, Hyun Chul(이현철)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111907
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