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뇌 자기공명영상에서 뇌간과 소뇌 계측을 이용한 다계통위축증과 파킨슨병의 감별 진단
DC Field | Value | Language |
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dc.contributor.author | 이명식 | - |
dc.date.accessioned | 2015-07-14T16:56:16Z | - |
dc.date.available | 2015-07-14T16:56:16Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1225-7044 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/111883 | - |
dc.description.abstract | Background: Multiple system atrophy (MSA) and idiopathic Parkinson’s disease (IPD) are two common neurodegenerative disorders presenting with parkinsonism. Since a brain MRI study is an available method for differentiating MSA from IPD, we tried to find further values of brain MRI studies in differentiating MSA from IPD. Methods: We measured anteroposterior and transverse diameters (AD and TD, respectively) of the brain stem of T2-weighted axial images. We graded the severity of atrophy (grade 0: none; grade 1: mild; grade 2: moderate; and grade 3: severe) of cerebellar vermis and hemispheres on the midsagittal and parasagittal planes. Results: There were 36 patients with probable MSA and 40 patients with IPD. We calculated a parameter multiplying AD of the midbrain by TD of the midbrain. The mean of the AD x TD of the midbrain was 1007.5±161.8 mm2 in patients with MSA, and it was significantly smaller than that of those with IPD (1113.3±118.7 mm2). When the cut off value was decided as 1050 mm2, the sensitivity of the parameter for the diagnosis of MSA was 83.3% and specificity was 80%. The frequency of cerebellar atrophy was 72.2% in patients with MSA, and it was significantly higher than that of those with IPD (37.5%). Conclusions: Measurements of the brain stem, particularly the midbrain, and cerebellum areas on brain MRI are helpful methods for the differential diagnosis of patients with MSA from those with IPD. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 478~484 | - |
dc.relation.isPartOf | Journal of the Korean Neurological Association | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 뇌 자기공명영상에서 뇌간과 소뇌 계측을 이용한 다계통위축증과 파킨슨병의 감별 진단 | - |
dc.title.alternative | Measurements of Brain Stem and Cerebellum on Brain MRI: for the Differential Diagnosis Between Multiple System Atrophy and Idiopathic Parkinson's Disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | 나상준 | - |
dc.contributor.googleauthor | 박지형 | - |
dc.contributor.googleauthor | 이명식 | - |
dc.contributor.googleauthor | 이기욱 | - |
dc.contributor.googleauthor | 홍지만 | - |
dc.contributor.googleauthor | 김현숙 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.relation.journalcode | J01835 | - |
dc.subject.keyword | Multiple system atrophy | - |
dc.subject.keyword | Idiopathic Parkinson's disease | - |
dc.subject.keyword | Brain magnetic resonance imaging | - |
dc.contributor.alternativeName | Lee, Myung Sik | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 22 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 478 | - |
dc.citation.endPage | 484 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Neurological Association, Vol.22(5) : 478-484, 2004 | - |
dc.identifier.rimsid | 47353 | - |
dc.type.rims | ART | - |
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