Cited 17 times in
Significance of chronic epilepsy in glial tumors and correlation with surgical strategies
DC Field | Value | Language |
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dc.contributor.author | 이규성 | - |
dc.contributor.author | 이병인 | - |
dc.date.accessioned | 2015-07-14T16:50:23Z | - |
dc.date.available | 2015-07-14T16:50:23Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0967-5868 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/111693 | - |
dc.description.abstract | PURPOSE: This study was designed to compare the frequency of postoperative epilepsy in patients with acute and chronic pre-operative epilepsy and with frontal or temporal lobe glial tumors based on the hypothesis that patients with chronic epilepsy do worse. METHODS: We compared the clinical and diagnostic characteristics of the patients (n = 73) who had seizures preoperatively with those of the patients (n = 153) who did not. Among those who have had seizures preoperatively, we compared those (n = 32, chronic seizure group) who had seizures a year or more prior to surgery with those (n = 41, acute seizure group) who had seizures less than a year prior to surgery. RESULTS: Among the various factors, the frequency of benign pathology and favorable neurological state were higher in the seizure group than in the non-seizure group (p < 0.05). Complex partial seizures and low-grade tumors were frequent in the chronic seizure group, whereas simple partial seizures and high-grade tumors were frequent in the acute seizure group. Seizure-free rate was significantly higher in the acute seizure group than in the chronic group (p < 0.05). Also, the difference of seizure control rate between surgical strategies was statistically significant (p < 0.05). CONCLUSION: This study indicates that preoperative seizure duration and frequency have a close relationship with the frequency of postoperative epilepsy in patients with glial tumors. A longer duration may allow the formation of epileptogenic foci, leading to chronic epilepsy, and eventually have a negative effect on the prognosis of the patients. Factors including histopathological characteristics of the tumor, its location, seizure duration/frequency, and symptomatology should be taken into account when deciding on surgical strategies. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 702~705 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL NEUROSCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Brain Neoplasms/complications* | - |
dc.subject.MESH | Brain Neoplasms/surgery | - |
dc.subject.MESH | Chronic Disease | - |
dc.subject.MESH | Epilepsy/etiology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glioma/complications* | - |
dc.subject.MESH | Glioma/surgery* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neurosurgical Procedures/adverse effects* | - |
dc.subject.MESH | Postoperative Period | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Significance of chronic epilepsy in glial tumors and correlation with surgical strategies | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | Ok-Joon Kim | - |
dc.contributor.googleauthor | Jung Yong Ahn | - |
dc.contributor.googleauthor | Byung-In Lee | - |
dc.contributor.googleauthor | Joong Uhn Choi | - |
dc.contributor.googleauthor | Kyu Sung Lee | - |
dc.contributor.googleauthor | Sang Sup Chung | - |
dc.contributor.googleauthor | Young Sun Chung | - |
dc.identifier.doi | 10.1016/j.jocn.2003.09.018 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.relation.journalcode | J01328 | - |
dc.identifier.eissn | 1532-2653 | - |
dc.identifier.pmid | 15337128 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0967586804001535 | - |
dc.subject.keyword | brain neoplasms | - |
dc.subject.keyword | glioma | - |
dc.subject.keyword | epilepsy | - |
dc.subject.keyword | surgical strategies | - |
dc.contributor.alternativeName | Lee, Kyu Sung | - |
dc.contributor.alternativeName | Lee, Byung In | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 11 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 702 | - |
dc.citation.endPage | 705 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL NEUROSCIENCE, Vol.11(7) : 702-705, 2004 | - |
dc.identifier.rimsid | 37418 | - |
dc.type.rims | ART | - |
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