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Volumetric investigation of the frontal-subcortical circuitry in patients with obsessive-compulsive disorder.
DC Field | Value | Language |
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dc.contributor.author | 김재진 | - |
dc.date.accessioned | 2015-07-14T16:38:20Z | - |
dc.date.available | 2015-07-14T16:38:20Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0895-0172 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/111290 | - |
dc.description.abstract | The pathophysiology of obsessive-compulsive disorder (OCD) is thought to involve disturbance of the frontal-subcortical circuitry. To investigate the morphological characteristics of this circuitry, we examined the volume of the orbitofrontal cortex, anterior cingulate, thalamus, caudate, and the putamen in 36 age- and sex-matched OCD patients and normal control subjects using three-dimensional magnetic resonance (MR) brain imaging. The left orbitofrontal volumes were found to be significantly smaller in the OCD patients and showed significant negative correlations with obsessive-compulsive symptom severity. These findings suggest that a structural abnormality of this brain region is implicated in the pathophysiology of OCD. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 342~349 | - |
dc.relation.isPartOf | JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Brain/pathology | - |
dc.subject.MESH | Brain Mapping | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Frontal Lobe/pathology* | - |
dc.subject.MESH | Functional Laterality/physiology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Processing, Computer-Assisted/methods | - |
dc.subject.MESH | Imaging, Three-Dimensional/methods | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/pathology* | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/physiopathology | - |
dc.title | Volumetric investigation of the frontal-subcortical circuitry in patients with obsessive-compulsive disorder. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | Do-Hyung Kang | - |
dc.contributor.googleauthor | Jae-Jin Kim | - |
dc.contributor.googleauthor | Jun Soo Kwon | - |
dc.contributor.googleauthor | Kee-Hyun Chang | - |
dc.contributor.googleauthor | Moon Hee Han | - |
dc.contributor.googleauthor | Tak Youn | - |
dc.contributor.googleauthor | Chi-Won Kim | - |
dc.contributor.googleauthor | Young Il Kim | - |
dc.contributor.googleauthor | Jung-Seok Choi | - |
dc.identifier.doi | 10.1176/appi.neuropsych.16.3.342 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.relation.journalcode | J01632 | - |
dc.identifier.eissn | 1545-7222 | - |
dc.identifier.pmid | 15377742 | - |
dc.identifier.url | http://neuro.psychiatryonline.org/article.aspx?articleid=101894 | - |
dc.contributor.alternativeName | Kim, Jae Jin | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 16 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 342 | - |
dc.citation.endPage | 349 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, Vol.16(3) : 342-349, 2004 | - |
dc.identifier.rimsid | 35961 | - |
dc.type.rims | ART | - |
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